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Remicade vs. Cimzia

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Remicade (infliximab) and Cimzia (certolizumab pegol) are both injectable medications used to treat autoimmune conditions, but they have some key differences. Remicade is given through an IV infusion by a healthcare provider, while Cimzia is injected under the skin and can be self-administered. Remicade is typically given every 6 to 8 weeks, whereas Cimzia is usually given every 2 to 4 weeks. Remicade is available only as a brand-name medication, which can be expensive, but it does have several biosimilars which may make it more affordable. Cimzia is also available as brand-name medication but offers the convenience of prefilled syringes. Both medications block a protein called tumor necrosis factor (TNF) to reduce inflammation. Remicade is approved for use in children 6 years and older for certain conditions, whereas Cimzia is not approved for use in children. Additionally, Remicade requires monitoring during and after infusions for side effects, while Cimzia users need to be trained on proper injection techniques. Both medications can increase the risk of serious infections and have similar side effects.

Remicade

(infliximab)

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Cimzia

(certolizumab)

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Summary for Remicade

Prescription only

Remicade (infliximab) is an injectable medication used to treat many autoimmune conditions, including ulcerative colitis and Crohn's disease. It's given through an intravenous (IV) infusion by a healthcare provider.

Indications for Remicade

  • Moderate-to-severe Crohn's disease (CD)
  • Moderate-to-severe ulcerative colitis (UC)
  • Moderate-to-severe rheumatoid arthritis (RA)
  • Ankylosing spondylitis (AS)
  • Psoriatic arthritis (PsA)
  • Severe plaque psoriasis (PsO)

Pros and Cons for Remicade

Pros

  • Can be used for many autoimmune conditions
  • Typically only needs to be given every 6 to 8 weeks
  • Can be used in children 6 years of age and older for UC and CD

Cons

  • Can only be given as an IV infusion by a healthcare professional
  • Can cause a lot of side effects
  • Brand name only, which can be expensive

Common Side Effects for Remicade

  • Infections
  • Nausea
  • Infusion-related reactions (e.g., headache, flushing, shortness of breath, rash)
  • Headache
  • Diarrhea
  • Stomach pain
  • Sore throat
  • Cough
  • Rash
  • Bronchitis
  • Indigestion
  • Tiredness
  • General pain
  • Joint pain

Warnings for Remicade

  • Serious or deadly infections
  • Cancer
  • Liver problems and liver failure
  • Heart problems
  • Low blood cell counts
  • Nervous system problems
  • Medications to avoid

Summary for Cimzia

Prescription only

Cimzia (certolizumab) is a prescription biologic used to treat several autoimmune conditions, like rheumatoid arthritis, psoriatic arthritis, and Crohn's disease. It works by blocking a protein called tumor necrosis factor (TNF), which helps reduce inflammation in your body. The medication is given as an injection under the skin every 2 to 4 weeks, depending on your condition. Common side effects include upper respiratory infections, urinary tract infections (UTIs), and skin rash.

Indications for Cimzia

Pros and Cons for Cimzia

Pros

  • Treats a variety of autoimmune conditions
  • Only need to inject every 2 to 4 weeks
  • Available as a prefilled syringe for at-home administration

Cons

  • Can raise your risk for infections
  • Some people might have difficulty injecting it properly
  • Might have a higher risk for certain cancers

Common Side Effects for Cimzia

Warnings for Cimzia

  • Serious infections
  • Cancer
  • Heart failure
  • Allergic reactions
  • Nervous system problems
  • Blood problems
  • Lupus-like condition
  • Live vaccines

Prices with our coupons for Remicade vs. Cimzia

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Remicade4 vials / 100mg
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Cimzia1 carton / 2 prefilled syringes of 200mg/ml
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