Key takeaways
Olopatadine (Pataday) and alcaftadine (Lastacaft) are both over-the-counter antihistamine eye drops used to treat eye itching and redness due to allergies. While both medications work as antihistamines and mast cell stabilizers, there are some differences between them. Olopatadine is available in different strengths and can be used once or twice daily depending on the strength, whereas alcaftadine (Lastacaft) is used just once daily. Olopatadine has a generic form, while alcaftadine (Lastacaft) does not. Common side effects of olopatadine include blurry vision and dry eye, while alcaftadine (Lastacaft) can cause eye irritation, burning, and stinging. Both medications require you to remove contact lenses before use and wait at least 10 minutes before reinserting them. Additionally, olopatadine might be more affordable compared to alcaftadine (Lastacaft).
