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Nasonex vs. Dymista

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Nasonex (mometasone) and Dymista (azelastine/fluticasone) are both nasal sprays used to treat allergy symptoms, but they have some key differences. Nasonex is a corticosteroid available both over-the-counter (OTC) and by prescription, while Dymista is a combination of an antihistamine (azelastine) and a corticosteroid (fluticasone) and is only available by prescription. Nasonex is used for relief of allergy symptoms, prevention of seasonal allergies, and treatment of nasal polyps, whereas Dymista is specifically for seasonal nasal allergies. Nasonex can be used in children as young as 2 years old (OTC) and 12 years old (prescription), while Dymista is approved for children 6 years and older. Dymista works faster, providing relief within 30 minutes, while Nasonex can take 1 to 2 weeks for full effects. Additionally, Dymista may cause drowsiness, unlike Nasonex. Both medications can cause nosebleeds and other side effects, but Dymista also has a risk of causing a bitter taste if it goes into your throat.

mometasone nasal spray

 

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Dymista

(azelastine / fluticasone)

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Summary for Nasonex

Prescription or over-the-counter

Mometasone nasal spray is used to prevent the nose symptoms of seasonal allergies, as well as to treat nose and sinus inflammation in adults with nasal polyps. Some side effects this medication can cause include headache and bloody nose. Mometasone nasal spray is available both with a prescription and over the counter (OTC).

Indications for Nasonex

  • Temporary relief of allergy symptoms (e.g., stuffy or runny nose, sneezing, itchy nose) (OTC only)
  • Prevention of seasonal allergies (prescription only)
  • Treatment of long-term nose and sinus inflammation with nasal polyps (prescription only)

Pros and Cons for Nasonex

Pros

  • Works well to prevent and treat allergy symptoms
  • Available OTC
  • Can be used to help control allergy symptoms in children 2 years or older (OTC only)
  • Available as a lower-cost generic with a prescription

Cons

  • Can take 1 to 2 weeks or longer to see the full effects
  • Doesn't have a counter on the spray bottle, so it can be hard to remember how many sprays are left
  • Can cause side effects like headache and nose bleeds in some people
  • Unknown if safe while pregnant or breastfeeding

Common Side Effects for Nasonex

  • Headache (26%)
  • Viral infection (14%)
  • Sore throat (12%)
  • Bloody nose or mucus (11%)
  • Coughing (7%)
  • Upper respiratory tract infection (i.e., common cold; 6%)
  • Period cramps (5%)
  • Muscle pain (5%)
  • Congestion, pressure near the nose or forehead, and other symptoms of sinus infection (5%)

Warnings for Nasonex

  • Nose injury and slowed wound healing
  • Fungal infection in the nose and throat
  • Vision changes
  • Risk of infection
  • Hormone changes
  • Poor growth in children

Summary for Dymista

Prescription only

Dymista is a combination nasal spray containing azelastine (an antihistamine) and fluticasone (a corticosteroid). It's used by people ages 6 years and older to treat nasal allergy symptoms, such as runny, stuffy, or itchy nose. The typical dose is to spray one spray into each nostril twice per day. Side effects aren't common, but include headache and a bad taste in the mouth. Dymista (azelastine / fluticasone) is available as both brand-name and generic medications.

Indications for Dymista

  • Nasal allergy symptoms (e.g., runny, stuffy, or itchy nose, sneezing, itchy or watery eyes)

Pros and Cons for Dymista

Pros

  • Combines two medications into a single spray
  • Starts to work within 30 minutes after the first dose
  • Likely safe to use during pregnancy

Cons

  • Prescription only
  • Need to use daily for 2 weeks to experience the full effects of fluticasone in Dymista
  • Need to use twice per day

Common Side Effects for Dymista

Warnings for Dymista

  • Sleepiness
  • Nose bleeds, discomfort, and injury
  • Risk of infection
  • Altered stress hormone levels
  • Delayed growth in children
  • Allergic reactions
  • Eye and vision problems

Prices with our coupons for Nasonex vs. Dymista

Price Card Drug Icon
Mometasone1 nasal spray / 17g of 50mcg
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Azelastine/Fluticasone1 nasal spray / 23g of 137mcg/50mcg
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