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Nasonex vs. Claritin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Nasonex (mometasone) and Claritin (loratadine) are both used to treat allergy symptoms, but they work in different ways and come in different forms. Nasonex is a corticosteroid nasal spray that reduces inflammation in your nose, while Claritin is an oral antihistamine that blocks histamine to relieve symptoms like runny nose and itchy eyes. Nasonex can be used for both short-term and long-term relief, including for nasal polyps, and is available both over-the-counter and by prescription. Claritin, on the other hand, is only available over-the-counter and is typically used for short-term relief of allergy symptoms. Nasonex may take 1 to 2 weeks to show full effects, whereas Claritin usually starts working within 1 to 3 hours. Common side effects of Nasonex include headaches and nosebleeds, while Claritin may cause headaches and drowsiness. Additionally, Nasonex is not known to cause drowsiness, unlike Claritin, which can make you sleepy, though less so than older antihistamines like Benadryl.

mometasone nasal spray

 

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Loratadine

(Claritin)

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Summary for Nasonex

Prescription or over-the-counter

Mometasone nasal spray is used to prevent the nose symptoms of seasonal allergies, as well as to treat nose and sinus inflammation in adults with nasal polyps. Some side effects this medication can cause include headache and bloody nose. Mometasone nasal spray is available both with a prescription and over the counter (OTC).

Indications for Nasonex

  • Temporary relief of allergy symptoms (e.g., stuffy or runny nose, sneezing, itchy nose) (OTC only)
  • Prevention of seasonal allergies (prescription only)
  • Treatment of long-term nose and sinus inflammation with nasal polyps (prescription only)

Pros and Cons for Nasonex

Pros

  • Works well to prevent and treat allergy symptoms
  • Available OTC
  • Can be used to help control allergy symptoms in children 2 years or older (OTC only)
  • Available as a lower-cost generic with a prescription

Cons

  • Can take 1 to 2 weeks or longer to see the full effects
  • Doesn't have a counter on the spray bottle, so it can be hard to remember how many sprays are left
  • Can cause side effects like headache and nose bleeds in some people
  • Unknown if safe while pregnant or breastfeeding

Common Side Effects for Nasonex

  • Headache (26%)
  • Viral infection (14%)
  • Sore throat (12%)
  • Bloody nose or mucus (11%)
  • Coughing (7%)
  • Upper respiratory tract infection (i.e., common cold; 6%)
  • Period cramps (5%)
  • Muscle pain (5%)
  • Congestion, pressure near the nose or forehead, and other symptoms of sinus infection (5%)

Warnings for Nasonex

  • Nose injury and slowed wound healing
  • Fungal infection in the nose and throat
  • Vision changes
  • Risk of infection
  • Hormone changes
  • Poor growth in children

Summary for Claritin

Over-the-counter

Loratadine (Claritin) is an over-the-counter antihistamine for adults and kids. It helps relieve allergy symptoms like a runny nose, sneezing, and watery eyes. This allergy medication is taken by mouth, usually once a day. It comes as different formulations, including regular tablets, chewable tablets, and a liquid. Loratadine (Claritin) is a non-drowsy allergy medication because it's less likely to make you sleepy. Other side effects can include headache and feeling tired. Loratadine (Claritin) is available as a brand-name and generic.

Indications for Claritin

  • Short-term relief of allergy symptoms (runny nose, itchy nose or throat, itchy or watery eyes)

Pros and Cons for Claritin

Pros

Cons

  • Can take 1 to 3 hours to start working
  • Regular tablets and quick-dissolving tablets not for children younger than 6
  • Might have a higher risk of side effects if you have liver or kidney problems

Common Side Effects for Claritin

  • Headache (12%)
  • Sleepiness (8%)
  • Feeling tired (4%)
  • Dry mouth (3%)

Warnings for Claritin

  • Sleepiness
  • Accidentally taking too much medication
  • Caution use in people with phenylketonuria (PKU) - chewable tablets and orally disintegrating tablets

Prices with our coupons for Nasonex vs. Claritin

Price Card Drug Icon
Mometasone1 nasal spray / 17g of 50mcg
$39.19$136.12
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Loratadine30 tablets / 24 hour
$8.59$8.93
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