Key takeaways
Movantik (naloxegol) and bisacodyl (Dulcolax) are both used to treat constipation, but they work in different ways and are used for different types of constipation. Movantik is an opioid antagonist that specifically treats constipation caused by opioid medications. It blocks opioid receptors in the intestines, helping you go to the bathroom more easily. You take it once daily on an empty stomach, and it is only available as a brand-name medication. Common side effects include stomach pain, diarrhea, and nausea. On the other hand, bisacodyl is a stimulant laxative used for occasional constipation and irregular bowel movements. It works by stimulating the muscles in your intestines and preventing your body from drawing too much water away from your guts, which helps soften the stool. Bisacodyl is available over-the-counter and comes in both tablet and suppository forms. It typically starts working within 6 to 12 hours, and common side effects include belly discomfort and cramps. Unlike Movantik, bisacodyl should not be taken for more than a week without consulting a healthcare provider.
