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Monopril vs. Altace

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Fosinopril (generic, brand name Monopril no longer available) and Ramipril (generic, brand name Altace no longer available) are both ACE inhibitors used to treat high blood pressure and heart failure. Fosinopril is typically taken once daily, while Ramipril can be taken once or twice daily depending on the dose. Fosinopril is also used to protect the kidneys in people with diabetes, a benefit not mentioned for Ramipril. Both medications can cause a dry cough and dizziness, but Ramipril is noted to cause headaches and feelings of tiredness more commonly. Fosinopril starts working within 1 hour and takes 1-2 weeks to fully kick in, whereas Ramipril starts lowering blood pressure within 1-2 hours but may take a few weeks to find the best dose. Both medications are not safe during pregnancy and can cause serious side effects like angioedema and high potassium levels. However, Ramipril has additional warnings for liver problems and lower blood cell counts.

Fosinopril

 

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Ramipril

 

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Summary for Monopril

Prescription only

Fosinopril sodium (Monopril) is an angiotensin-converting enzyme (ACE) inhibitor. It's used to treat high blood pressure in adults and children. It can also treat heart failure. Fosinopril comes as a tablet that's taken by mouth once daily. Most people don't experience any side effects from fosinopril. But people who did reported cough and dizziness. Though rare, fosinopril and other ACEI inhibitors can cause angioedema, which can be serious. Brand name Monopril has been discontinued; fosinopril is only available as a generic medication.

Indications for Monopril

Pros and Cons for Monopril

Pros

  • Taken by mouth
  • Taken once a day
  • Available as a lower-cost generic

Cons

  • Can cause a cough that might not go away until you stop the medication
  • Not safe to use if you're pregnant
  • Might not work as well for lowering high blood pressure in Black adults

Common Side Effects for Monopril

For the treatment of high blood pressure

  • Cough (2%)
  • Dizziness (2%)
  • Nausea or vomiting (1%)

For the treatment of heart failure

  • Dizziness (12%)
  • Cough (10%)
  • Low blood pressure (4%)
  • Muscle pain (3%)
  • Nausea or vomiting (2%)
  • Diarrhea (2%)
  • Chest pain (2%)
  • Upper respiratory tract infection (2%)

Warnings for Monopril

  • Not safe during pregnancy
  • Angioedema (swelling) and serious allergic reactions
  • Risk of infection (lower white blood cell count)
  • Low blood pressure
  • Worsening kidney problems
  • High potassium levels
  • Risk of liver problems

Summary for Altace

Prescription only

Ramipril is an angiotensin-converting enzyme (ACE) inhibitors. This medication treats high blood pressure by relaxing blood vessels. It can also ease heart failure symptoms after a heart attack. Ramipril is taken by mouth, typically once or twice daily, by adults. Some of the more common side effects of this medication include headache, dizziness, and feeling tired. Ramipril is generic only because the brand name Altace is no longer available.

Indications for Altace

Pros and Cons for Altace

Pros

  • Taken by mouth
  • Capsules can be opened and sprinkled on applesauce or water for those with trouble swallowing
  • Available as a lower-cost generic

Cons

Common Side Effects for Altace

High blood pressure

  • Headache (5%)
  • Dizziness (2%)
  • Feeling tired or weak (2%)

Heart failure after heart attack

  • Low blood pressure (11%)
  • Cough (8%)
  • Dizziness (4%)

Warnings for Altace

  • Not for use during pregnancy
  • Angioedema (swelling)
  • Severe allergic reaction
  • Liver problems
  • Worsening kidney problems
  • Lower blood cell counts
  • Low blood pressure
  • Heart problems due to high potassium
  • Cough

Prices with our coupons for Monopril vs. Altace

Price Card Drug Icon
Fosinopril90 tablets / 40mg
$25.81$104.80
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Ramipril90 capsules / 10mg
$10.00$10.00
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