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Minocycline vs. Clindesse

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Minocycline (Minocin, Minolira, Solodyn, Ximino) and clindamycin (Clindesse, Cleocin, Xaciato) are both antibiotics used to treat bacterial infections, but they belong to different medication classes. Minocycline is a tetracycline antibiotic, while clindamycin is a lincosamide antibiotic. Minocycline is used to treat a wide range of infections, including acne, respiratory tract infections, and sexually transmitted infections, and is available in oral forms. Clindamycin, on the other hand, is specifically used for vaginal bacterial infections and is available as a vaginal cream or gel. Minocycline can cause side effects like headache, dizziness, and increased sensitivity to sunlight, while clindamycin may lead to vaginal discomfort and yeast infections. Minocycline can interact with blood thinners and birth control pills, whereas clindamycin can weaken condoms and diaphragms. Minocycline is available as a generic, making it more affordable, while some forms of clindamycin are only available as brand-name medications.

Minocycline

 

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clindamycin vaginal cream

 

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Summary for Minocycline

Prescription only

Immediate-release minocycline is a tetracycline antibiotic used to treat many types of bacterial infections in adults and children 8 years and older. These include urinary tract infections (UTIs), sinus infections, and even severe acne. It comes as a tablet or capsule, and is usually taken by mouth every 12 hours. Common side effects include headache, tiredness, and dizziness.

Indications for Minocycline

Pros and Cons for Minocycline

Pros

  • Can take with or without food
  • Treats many different types of bacterial infections
  • A good alternative if you're allergic to penicillin
  • Taken twice a day

Cons

  • Can make your skin more sensitive to sunlight
  • Can stain children's teeth during tooth development
  • Interacts with blood thinners and birth control pills
  • Not safe in pregnancy or breastfeeding

Common Side Effects for Minocycline

Warnings for Minocycline

  • Harm to unborn babies
  • Tooth discoloration
  • Slow bone growth
  • Infectious diarrhea
  • Severe allergic and serious skin reactions
  • Kidney and liver damage
  • Brain and nerve effects
  • High pressure in the brain
  • Autoimmune problems
  • Sun sensitivity
  • Darkening of body tissues
  • New infection

Summary for Clindesse

Prescription only

Clindamycin vaginal cream is an antibiotic used to treat bacterial vaginosis (BV). It’s available under two brand names, Clindesse and Cleocin, and applied inside the vagina using an applicator. Clindesse is a single-dose treatment used one time, while Cleocin and its generic versions are typically used once a day at bedtime for 3 or 7 days. Common side effects include vaginal irritation and yeast infections.

Indications for Clindesse

Pros and Cons for Clindesse

Pros

  • Applied directly in the vagina to treat the problem where it is
  • Easy to apply using the applicator
  • Available as both single-dose (Clindesse) and multi-day (Cleocin) options

Cons

  • Can cause yeast infections
  • Can't use condoms, diaphragms, or tampons for several days after finishing treatment
  • Possible irritation or discomfort

Common Side Effects for Clindesse

Clindesse:

  • Vaginal yeast infection (14%)
  • Headache (7%)
  • Back pain (5%)
  • Constipation (2%)
  • Urinary tract infection (2%)

Cleocin and its generics:

  • Vaginal yeast infection (8-14%)
  • Vaginal irritation (4-6%)
  • Vaginal problems (3-5%)

Warnings for Clindesse

  • Severe diarrhea
  • Damage to condoms and diaphragms

Prices with our coupons for Minocycline vs. Clindesse

Price Card Drug Icon
Minocycline30 capsules / 100mg
$20.36$29.85
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Price Card Drug Icon
Clindesse1 applicator / 5.8g of 2%
$109.25$193.81
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