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Miebo vs. Restasis

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Miebo

(perfluorohexyloctane)

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Cyclosporine

(Restasis)

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Summary for Miebo

Prescription only

Miebo (perfluorohexyloctane) is a prescription eye drop that's used to treat dry eyes in adults. It's a semifluorinated alkane eye drop that forms a layer on the eye(s) to prevent tears from drying out. The most common side effects of Miebo (perfluorohexyloctane) are blurry vision and eye redness. Currently, it's only available under the brand name Miebo.

Indications for Miebo

Pros and Cons for Miebo

Pros

  • Preservative-free
  • Not many side effects
  • Stored at room temperature, which is convenient for traveling

Cons

  • Needs to be applied 4 times a day
  • Not known if safe for use in children
  • Can cause blurred vision and eye redness

Common Side Effects for Miebo

  • Blurred vision (1-3%)
  • Eye redness (1-3%)

Warnings for Miebo

  • Use with contact lenses

Summary for Restasis

Prescription only

Cyclosporine eye drops, also known by the brand names Restasis and Restasis MultiDose, treat dry eye in people 16 years and older. It's an immunosuppressant called a calcineurin inhibitor, and it helps with tear production. Cyclosporine (Restasis) comes in single-use vials and multi-dose bottles. Only the single-use vials have a generic version. The eye drops are used twice every day. The most common side effect is a burning feeling in the eye, which usually gets better as you continue to use the medication.

Indications for Restasis

  • Dry eye in people 16 years and older

Pros and Cons for Restasis

Pros

  • Helps your eye make its own tears
  • Can use with other lubricating eye drops, such as artificial tears
  • Available as single-use vials and multi-dose bottles

Cons

  • Need to use twice a day
  • Can take a long time (up to 6 months) to see improvement in dry eyes
  • Commonly causes a burning sensation in the eye

Common Side Effects for Restasis

  • Burning sensation in the eye (17%)

Warnings for Restasis

  • For use in the eye only
  • Avoid use with contact lenses

Prices with our coupons for Miebo vs. Restasis

Price Card Drug Icon
Miebo1 dropper / 3ml of 1.338g/ml
$809.68$990.99
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Price Card Drug Icon
Cyclosporine1 package / 60 vials of 0.4ml
$62.46$698.06
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