Skip to main content

Compare
Metformin vs. Victoza

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Metformin (Glucophage) and Victoza (liraglutide) are both prescription medications used to manage Type 2 diabetes, but they work in different ways and have different forms of administration. Metformin is an oral medication that helps lower blood sugar by reducing the amount of sugar your body makes or absorbs. It’s usually taken once or twice daily with food to minimize stomach side effects like diarrhea and nausea. On the other hand, Victoza is a GLP-1 agonist that is injected once daily and works by telling your body to release more insulin, stopping the release of more sugar, and slowing down digestion. While both medications can help lower blood sugar levels, Victoza also has the added benefit of potentially reducing the risk of major heart-related problems in adults with Type 2 diabetes and heart disease. Victoza can cause side effects like nausea, vomiting, and injection site reactions, while metformin can cause diarrhea and nausea. While metformin is safe for use during pregnancy, Victoza should be avoided.

Metformin

 

Get free coupons

Victoza

(liraglutide)

Get free coupons

Summary for Metformin

Prescription only

Immediate-release metformin is an oral diabetes medication. It's approved for people 10 years of age and older with Type 2 diabetes. The medication belongs to the drug class called biguanides. It works best to lower blood sugar levels with a diabetes-friendly diet and exercise plan. Immediate-release metformin comes as a tablet and an oral solution. You take this medication by mouth usually two to three times a day. It's recommended to take each dosage with food to help lessen side effects like diarrhea and nausea.

Indications for Metformin

Pros and Cons for Metformin

Pros

Cons

  • Typically need to take a couple times per day
  • Can cause stomach upset, including diarrhea, nausea, gas, and stomach cramping
  • Not a good choice for people with severe kidney problems
  • Not recommended for people with liver problems

Common Side Effects for Metformin

  • Diarrhea (53%)
  • Nausea or vomiting (26%)
  • Gas (12%)
  • Weakness (9%)

Warnings for Metformin

  • Lactic acidosis
  • Low vitamin B12 levels
  • Low blood sugar (hypoglycemia) when taken with certain other diabetes medications

Summary for Victoza

Prescription only

Victoza (liraglutide) is a medication that's injected once a day. It helps lower blood sugar levels in people 10 years and older with Type 2 diabetes when used with a nutritious diet and regular exercise. It can also help lower the risk of heart-related problems in adults with Type 2 diabetes and heart disease. Victoza (liraglutide) belongs to the drug class called GLP-1 agonists. The medication comes as single-dose prefilled pens and is injected under the skin. It can cause side effects like nausea, vomiting, diarrhea, and constipation. Victoza (liraglutide) is available as both a brand-name and generic medication.

Indications for Victoza

  • Type 2 diabetes in people age 10 and older, together with a balanced diet and exercise
  • Lowering the risk of serious heart-related problems in adults with Type 2 diabetes and heart disease

Pros and Cons for Victoza

Pros

  • Lowers A1C by up to 1% over a year
  • Can take with or without food at any time of day
  • Available as an injectable pen

Cons

Common Side Effects for Victoza

Warnings for Victoza

  • Possible risk of thyroid cancer
  • Inflammation of the pancreas (pancreatitis)
  • Low blood sugar (hypoglycemia)
  • Kidney damage
  • Allergic reactions
  • Gallbladder problems
  • Lung problems during general anesthesia or deep sedation

Prices with our coupons for Metformin vs. Victoza

Price Card Drug Icon
Metformin60 tablets / 500mg
$9.00$9.00
Get free coupons
More Information
Price Card Drug Icon
Liraglutide (Victoza)1 carton / 3 pens of 18mg/3ml
$201.30$923.83
Get free coupons
More Information

Browse medications by letter

Show All

Browse prescription and over-the-counter medications from A to Z, compare drug prices, and start saving.