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Lovenox vs. Eliquis

Enoxaparin (Lovenox) is a blood thinner that's used to treat and prevent blood clots and other clotting-related conditions. It's given as an injection under the skin in the stomach. The dosing for enoxaparin (Lovenox) depends mostly on your weight, but also on why you need the medication. Enoxaparin (Lovenox) is a preferred choice for pregnant women, but it might not be the best option if they have prosthetic (artificial) heart valves. Side effects aren't common, but can include bleeding or bruising at the injection site. Enoxaparin (Lovenox) is available as a brand and generic medication.

• Prevention of blood clots in the arms or legs (deep vein thrombosis or DVT) or in the lungs (pulmonary embolism or PE) in:
  • People having stomach, hip, or knee surgery
  • People who aren't able to move well
  • People with a certain type of chest pain called unstable angina
• Treatment of blood clots
• Heart attack

• Abnormal liver tests (6%)
• Major bleeding (up to 4%)

• Risk of bleeding around the spinal cord during other injections near the spine
• Risk of bleeding
• Low platelet counts and clotting problems
• Higher risk of clots in pregnant women with prosthetic heart valves
• Risk of serious breathing problem in infants (gasping syndrome)

Eliquis (apixaban) is an anticoagulant (blood thinner) used to prevent and treat blood clots. It can lower the risk of serious conditions like stroke, deep vein thrombosis (DVT), and pulmonary embolism (PE). The medication comes as a tablet or liquid and is taken by mouth twice a day. Common side effects include bleeding and bruising. Although generic versions have been approved by the FDA, they might not be available until 2026.

Adults:

• Lower the risk of stroke or blood clots in people with atrial fibrillation (AFib) not caused by a heart valve problem
• Treat blood clots in the legs (deep vein thrombosis (DVT)) or lungs (pulmonary embolism (PE))
• Prevent DVT and PE after knee or hip replacement surgery
• Lower the risk of DVT or PE coming back after treatment

Children:

• Treat blood clots and lower the risk of new clots in children from birth and older

Adults:

• Any bleeding (up to 15%)

Children:

• Any bleeding (up to 36%)
• Headache (16%)
• Vomiting (14%)

• Higher risk of blood clots if stopped too early
• Paralysis in the spine
• Bleeding
• Not recommended in people with prosthetic heart valves
• Not recommended in people with antiphospholipid syndrome