Lialda vs. Apriso for Ulcerative Colitis: Important Differences and Potential Risks.

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Asacol HD, Lialda, And Delzicol For Ulcerative Colitis: What’S The Difference?

Mesalamine DR

(Lialda)

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Mesalamine

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Summary for Lialda

Prescription only

Mesalamine DR (Lialda) is an aminosalicylate that's used to treat mild-to-moderate ulcerative colitis (UC) in adults and children. It's a delayed-release (DR) tablet that's taken by mouth once daily with food. Side effects aren't common but can include headache and stomach upset. Mesalamine DR (Lialda) also has a risk for serious skin rash and sensitivity to the sun (e.g., might sunburn more easily).

Indications for Lialda

Mild-to-moderate ulcerative colitis (UC) in adults and children weighing at least 53 lbs

Pros and Cons for Lialda

Pros

Taken by mouth once daily
Available as a generic

Cons

Need to take with food
Only available as an extended-release tablet that can't be crushed, broken, or chewed

Common Side Effects for Lialda

Headache (3%)
Stomach pain (2%)
Diarrhea (2%)
Abnormal liver enzyme levels (2%)

Warnings for Lialda

Kidney damage and kidney stones
Acute intolerance syndrome
Severe allergic reactions
Severe skin reactions
Liver problems
Caution in people with gut blockage
Skin that's sensitive to sun and light

Summary for Apriso

Prescription only

Mesalamine is used to help with an inflammatory bowel disease called ulcerative colitis (UC). It helps relieve symptoms of mild or moderate UC, such as stomach pain, diarrhea, and gut inflammation. This medication can also be used to maintain remission (prevent UC flare-ups) in adults. There are many brand names for mesalamine on the market, and they all have lower-cost generics available. The dosage depends on the brand and formulation of mesalamine you have. In general, this medication can cause side effects like headache and indigestion.

Indications for Apriso

Ulcerative colitis (UC)

Pros and Cons for Apriso

Pros

Easy to take since it's a pill that's swallowed
Generally mild side effects
A first-choice option for preventing flare-ups in adults with mild UC
Lower-cost generics available

Cons

Typically need to take a few pills for each dose
Can take a few weeks before you start to feel the effects
Might cause kidney stones and make your skin more sensitive to the sun
Might not be the best option for people with liver problems

Common Side Effects for Apriso

Headache
Stomach pain
Nausea
Diarrhea
Indigestion

Warnings for Apriso

Kidney problems, including kidney stones
Abnormal reaction to mesalamine
Liver problems
Allergic reactions and severe skin reactions
Iron content in certain tablets and capsules of mesalamine
Caution use in people with phenylketonuria (for Apriso extended-release capsules only)

Prices with our coupons for Lialda vs. Apriso

Mesalamine DR60 tablets / 1.2g

$55.91$166.27

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Mesalamine DR60 tablets / 1.2g

$55.91$166.27

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Lialda vs. Apriso

Key takeaways

See more from our pharmacists

Mesalamine DR

Mesalamine

Summary for Lialda

Indications for Lialda

Pros and Cons for Lialda

Pros

Cons

Common Side Effects for Lialda

Warnings for Lialda

Summary for Apriso

Indications for Apriso

Pros and Cons for Apriso

Pros

Cons

Common Side Effects for Apriso

Warnings for Apriso

Prices with our coupons for Lialda vs. Apriso

Compare other Ulcerative Colitis drugs

Browse medications by letter

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Mesalamine DR

Mesalamine

Summary for Lialda

Indications for Lialda

Pros and Cons for Lialda

Pros

Cons

Common Side Effects for Lialda

Warnings for Lialda

Summary for Apriso

Indications for Apriso

Pros and Cons for Apriso

Pros

Cons

Common Side Effects for Apriso

Warnings for Apriso