Aminosalicylates are used to treat ulcerative colitis. Some can also help manage rheumatoid arthritis. Aminosalicylates work by reducing inflammation in the lining of the intestines, which helps to control symptoms like diarrhea, rectal bleeding, and abdominal pain. These medications come in different forms, including oral pills and rectal suppositories or enemas. Examples include mesalamine delayed-release (Lialda, Delzicol), sulfasalazine (Azulfidine), mesalamine suppository (Canasa), mesalamine enema (Rowasa), mesalamine extended-release (Pentasa, Apriso), and balsalazide (Colazal). You can choose the form that best fits your needs.