Key takeaways
Lexapro (escitalopram) and Buspar (buspirone) are FDA approved to treat anxiety. But they’re not in the same medication class. Lexapro (escitalopram) is a selective serotonin reuptake inhibitor (SSRI) that’s also FDA approved for depression. It works by increasing serotonin levels in the brain. Buspar also works by affecting serotonin, but it’s not an SSRI. Buspar is typically taken twice a day, while Lexparo is typically taken once a day. Lexapro is considered a first-choice medication for anxiety. Buspar is typically only added to SSRIs for anxiety (or other first-choice medications) if anxiety symptoms aren’t fully controlled with an SSRI alone. Common Lexapro side effects include nausea, insomnia, and sexual problems. It can also lead to withdrawal symptoms if stopped abruptly. Buspar can cause dizziness and headaches. It isn’t known to cause withdrawal symptoms.
