Key takeaways
Galantamine (Razadyne ER) and rivastigmine (Exelon) are both acetylcholinesterase inhibitors used to treat Alzheimer's disease, but they have some differences. Galantamine is only approved for mild-to-moderate Alzheimer's, while rivastigmine can also be used for dementia related to Parkinson's disease. Galantamine is available as a tablet, oral solution, and extended-release capsule, whereas rivastigmine comes in an oral capsule and a skin patch. The skin patch option for rivastigmine can be helpful if you have trouble swallowing pills. Both medications can cause nausea and vomiting, but these side effects are more common with rivastigmine. Rivastigmine also has a risk of causing certain movement problems, especially in people with Parkinson's disease. Additionally, galantamine needs to be taken with food to reduce stomach side effects, while rivastigmine capsules should also be taken with meals, and the patch should be applied to clean, dry skin.
