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Fosamax vs. Miacalcin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Alendronate

(Fosamax)

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calcitonin salmon

 

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Summary for Fosamax

Prescription only

Alendronate sodium (Fosamax) is a bisphosphonate that prevents and treats osteoporosis. It works by slowing the breakdown of bones so that the body has a chance to build up more bone; this strengthens bones and lowers the risk of fractures. Alendronate (Fosamax) is taken by mouth, either daily or weekly dosing, depending on your dose. In addition to the tablet, it's also available as an oral solution and a dissolvable tablet (brand name Binosto). Some common side effects of alendronate (Fosamax) can include stomach pain, heartburn, and bone or muscle pain.

Indications for Fosamax

Pros and Cons for Fosamax

Pros

Cons

  • Can't lie down for 30 minutes after you take it
  • Must take on empty stomach, can't eat for 30 minutes after a dose
  • Can cause serious jaw problems and severe muscle or joint pain
  • Has many stomach-related side effects

Common Side Effects for Fosamax

  • Stomach pain (up to 7%)
  • Muscle, bone, and joint pain (up to 4%)
  • Heartburn or indigestion (up to 4%)
  • Nausea (up to 4%)
  • Passing gas (up to 4%, more common with daily dose)

Warnings for Fosamax

  • Irritation and ulcers of the stomach and esophagus
  • Lower calcium levels
  • Muscle Pain
  • Jaw bone problems
  • Leg bone fractures
  • Not recommended in people with serious kidney problems

Summary for Miacalcin

Prescription only

Calcitonin salmon is a synthetic (man-made) hormone available as a nasal spray. It's used to treat osteoporosis in women who have already gone through menopause (postmenopause). The medication is typically taken once a day by alternating between nostrils each day. Common side effects include back pain and nose symptoms, like runny nose, irritation, and bleeding. The nasal spray used to be available under the brand name Miacalcin, but now only comes as a generic version.

Indications for Miacalcin

  • Osteoporosis in women who have gone through menopause (postmenopause)

Pros and Cons for Miacalcin

Pros

  • Only need to use it once a day
  • Can store a used bottle at room temperature for about a month
  • Available as a lower-cost generic medication

Cons

  • Not a first-choice treatment option for postmenopausal osteoporosis
  • Can lead to low calcium levels
  • Might raise the risk of certain cancers

Common Side Effects for Miacalcin

  • Runny nose (12%)
  • Nose irritation, dryness, redness (11%)
  • Back pain (5%)
  • Joint pain (4%)
  • Bloody nose (4%)

Warnings for Miacalcin

  • Severe allergic reaction
  • Low calcium (hypocalcemia)
  • Nasal irritation
  • Cancer

Prices with our coupons for Fosamax vs. Miacalcin

Price Card Drug Icon
Alendronate3 dose packs / 4 tablets of 70mg
$17.08$79.01
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Calcitonin Salmon1 nasal spray / 3.7ml of 200iu/spray
$32.38$46.89
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