Key takeaways
Dexmethylphenidate (Focalin, Focalin XR) and Adderall XR (Adderall XR, Mydayis) are both stimulant medications used to treat attention deficit-hyperactivity disorder (ADHD). They work by increasing certain chemicals in the brain, like norepinephrine and dopamine, to help improve focus and attention. Both medications are controlled substances due to their risk of misuse and dependency. However, they differ in several ways. Dexmethylphenidate is available in both immediate-release and extended-release forms, while Adderall XR and Mydayis are only available as extended-release. Dexmethylphenidate is available as a lower-cost generic, whereas Mydayis is only available as a brand medication. The starting doses and maximum doses also vary between the two medications. Common side effects for both include trouble sleeping and loss of appetite, but dexmethylphenidate can also cause stomach upset and nervousness, while Adderall XR may lead to dry mouth and weight loss. Both medications can interact with other drugs, especially those affecting serotonin levels, and should not be taken with monoamine oxidase inhibitors (MAOIs).
