Compare Evenity vs. Alendronate
Head-to-head comparisons of medication uses, side effects, warnings, and more.
- Evenity (romosozumab)Alendronate (Fosamax)
- Evenity (romosozumab)Alendronate (Fosamax)
Summary of Evenity vs. Alendronate
Summary for Sclerostin inhibitorPrescription onlyEvenity (romosozumab or romosozumab-aqqg) is an injection used to treat osteoporosis (bone loss) in certain women after menopause. These women either have a high risk of fracture or can’t take other medications for bone loss. It's also used when these other medications haven’t worked well enough. Evenity (romosozumab) belongs to the drug class called sclerostin inhibitors. It works to help your bones grow and prevent bone breakdown at the same time. The injection is given once a month by a healthcare professional. Common side effects are joint pain and headache. There's also serious risks of heart attack and stroke. This medication is brand name only; there's no generic available yet.
Summary for BisphosphonatePrescription onlyAlendronate sodium (Fosamax) is a bisphosphonate that prevents and treats osteoporosis. It works by slowing the breakdown of bones so that the body has a chance to build up more bone; this strengthens bones and lowers the risk of fractures. Alendronate (Fosamax) is taken by mouth, either daily or weekly dosing, depending on your dose. In addition to the tablet, it's also available as an oral solution and a dissolvable tablet (brand name Binosto). Some common side effects of alendronate (Fosamax) can include stomach pain, heartburn, and bone or muscle pain.
Indications of Evenity vs. Alendronate
Indications for•Treatment of osteoporosis in certain women after menopause•With high risk of fracture•Who can’t take other medications for bone loss•Who tried other medications for bone loss that didn’t workIndications for•Prevention and treatment of osteoporosis in females•Treatment of osteoporosis in malesPros and Cons of Evenity vs. Alendronate
Pros and Const for Sclerostin inhibitorPros•Helps with bone growth and prevents bone loss at the same time•Given just once a month•Only need 1 year of treatmentCons•Needs to be injected•Must go to the medical office for each injection•Bone mineral density eventually goes back to where it was before after stopping the medicationPros and Const for BisphosphonatePros•Can be taken by males and females (unlike another bisphosphonate)•Option for daily or weekly dosing for osteoporosis•Taken by mouthCons•Can't lie down for 30 minutes after you take it•Must take on empty stomach, can't eat for 30 minutes after a dose•Can cause serious jaw problems and severe muscle or joint pain•Has many stomach-related side effectsCommon Side Effects of Evenity vs. Alendronate
Common Side Effects for•Joint pain (up to 13%)•Headache (up to 7%)Common Side Effects for•Stomach pain (up to 7%)•Muscle, bone, and joint pain (up to 4%)•Heartburn or indigestion (up to 4%)•Nausea (up to 4%)•Passing gas (up to 4%, more common with daily dose)Warnings of Evenity vs. Alendronate
Common Side Effects for•Risk of heart attack, stroke, or heart-related death•Low calcium levels (hypocalcemia)•Risk of problems in the jawbone (osteonecrosis of the jaw)•Risk of fractures in the thighCommon Side Effects for•Irritation and ulcers of the stomach and esophagus•Lower calcium levels•Muscle Pain•Jaw bone problems•Leg bone fractures•Not recommended in people with serious kidney problemsPrices with our coupons for Evenity vs. Alendronate
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