Evenity vs. Tymlos for Osteoporosis: Important Differences and Potential Risks.

Evenity

(romosozumab)

Tymlos

(abaloparatide)

Summary for Evenity

Prescription only

Evenity (romosozumab or romosozumab-aqqg) is an injection used to treat osteoporosis (bone loss) in certain women after menopause. These women either have a high risk of fracture or can’t take other medications for bone loss. It's also used when these other medications haven’t worked well enough. Evenity (romosozumab) belongs to the drug class called sclerostin inhibitors. It works to help your bones grow and prevent bone breakdown at the same time. The injection is given once a month by a healthcare professional. Common side effects are joint pain and headache. There's also serious risks of heart attack and stroke. This medication is brand name only; there's no generic available yet.

Indications for Evenity

Treatment of osteoporosis in certain women after menopause
- With high risk of fracture
- Who can’t take other medications for bone loss
- Who tried other medications for bone loss that didn’t work

Pros and Cons for Evenity

Pros

Helps with bone growth and prevents bone loss at the same time
Given just once a month
Only need 1 year of treatment

Cons

Needs to be injected
Must go to the medical office for each injection
Bone mineral density eventually goes back to where it was before after stopping the medication

Common Side Effects for Evenity

Joint pain (up to 13%)
Headache (up to 7%)

Warnings for Evenity

Risk of heart attack, stroke, or heart-related death
Low calcium levels (hypocalcemia)
Risk of problems in the jawbone (osteonecrosis of the jaw)
Risk of fractures in the thigh

Summary for Tymlos

Prescription only

Tymlos (abaloparatide) is a medication used for osteoporosis in men and postmenopausal women at high risk for breaking bones (fractures). It's given once per day as an injection under the skin. This medication can't be used for longer than 2 years because of a theoretical risk of causing bone cancer.

Indications for Tymlos

Osteoporosis in women who have gone through menopause (postmenopause)
Osteoporosis in men

Pros and Cons for Tymlos

Pros

Available as a pre-filled pen with 30 doses
Good choice for men and postmenopausal women with osteoporosis at high risk for fracture or who've previously tried other osteoporosis medications
Can keep at room temperature after its first use for up to 30 days, making it convenient to take it on the go

Cons

Needs to be injected under the skin once per day
Not approved for osteoporosis from long-term corticosteroid use
Can't use for longer than 2 years

Common Side Effects for Tymlos

Redness at injection site (up to 58%)
Swelling at injection site (up to 10%)
Dizziness (up to 10%)
Pain at injection site (up to 9%)
Nausea (up to 8%)

*Percentages of people who reported these side effects might differ between men and postmenopausal women taking this medication.

Warnings for Tymlos

Bone cancer
Sudden low blood pressure (orthostatic hypotension)
High blood calcium levels
Kidney stones

Prices with our coupons for Evenity vs. Tymlos

Evenity1 carton / 2 syringes of 105mg/1.17ml

Get free coupons

More Information

Tymlos1 pen / 1.56ml of 80mcg/dose

$2,883.03$4,169.46

Get free coupons

More Information

Browse medications by letter

Show All

Browse prescription and over-the-counter medications from A to Z, compare drug prices, and start saving.

Compare
Evenity vs. Tymlos

Evenity

Tymlos

Summary for Evenity

Indications for Evenity

Pros and Cons for Evenity

Pros

Cons

Common Side Effects for Evenity

Warnings for Evenity

Summary for Tymlos

Indications for Tymlos

Pros and Cons for Tymlos

Pros

Cons

Common Side Effects for Tymlos

Warnings for Tymlos

Prices with our coupons for Evenity vs. Tymlos

Compare other Osteoporosis drugs

Browse medications by letter

Good news for your inbox

Evenity

Tymlos

Summary for Evenity

Indications for Evenity

Pros and Cons for Evenity

Pros

Cons

Common Side Effects for Evenity

Warnings for Evenity

Summary for Tymlos

Indications for Tymlos

Pros and Cons for Tymlos

Pros

Cons

Common Side Effects for Tymlos

Warnings for Tymlos