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Compare Evenity vs. Boniva

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Evenity (romosozumab)
    Ibandronate (Boniva)
  • Evenity (romosozumab)
    Ibandronate (Boniva)

  • Summary of Evenity vs. Boniva

    Summary for Sclerostin inhibitor
    Prescription only

    Evenity (romosozumab or romosozumab-aqqg) is an injection used to treat osteoporosis (bone loss) in certain women after menopause. These women either have a high risk of fracture or can’t take other medications for bone loss. It's also used when these other medications haven’t worked well enough. Evenity (romosozumab) belongs to the drug class called sclerostin inhibitors. It works to help your bones grow and prevent bone breakdown at the same time. The injection is given once a month by a healthcare professional. Common side effects are joint pain and headache. There's also serious risks of heart attack and stroke. This medication is brand name only; there's no generic available yet.

    Summary for Bisphosphonate
    Prescription only

    Ibandronate (Boniva) is used to treat and prevent osteoporosis (bone loss or weakening). It can help improve bone mineral density (BMD) and lower the risk of back fractures. Unlike other similar osteoporosis medications, ibandronate (Boniva) is only approved for women who have gone through menopause.

  • Indications of Evenity vs. Boniva

    Indications for
    •Treatment of osteoporosis in certain women after menopause
    •With high risk of fracture
    •Who can’t take other medications for bone loss
    •Who tried other medications for bone loss that didn’t work
    Indications for
    •Osteoporosis in women who have gone through menopause (postmenopause)

  • Pros and Cons of Evenity vs. Boniva

    Pros and Const for Sclerostin inhibitor
    Pros
    •Helps with bone growth and prevents bone loss at the same time
    •Given just once a month
    •Only need 1 year of treatment
    Cons
    •Needs to be injected
    •Must go to the medical office for each injection
    •Bone mineral density eventually goes back to where it was before after stopping the medication
    Pros and Const for Bisphosphonate
    Pros
    •Taken once a month as a tablet
    •Also available as an IV infusion given by a healthcare provider every 3 months if there are too many stomach problems from the tablet
    •Helps lower the risk of back fractures
    •Available as a lower-cost generic medication
    Cons
    •Risk of many side effects, including stomach pain and severe jaw problems
    •Not approved for osteoporosis caused by long-term corticosteroid use, men with osteoporosis, or people with Paget's disease
    •Not recommended for people with severe kidney disease

  • Common Side Effects of Evenity vs. Boniva

    Common Side Effects for
    •Joint pain (up to 13%)
    •Headache (up to 7%)
    Common Side Effects for
    •Stomach pain (8%)
    •Heartburn (6%)
    •Joint pain (6%)
    •Back pain (5%)
    •Nausea (5%)
    •Diarrhea (5%)
    •Arm or leg pain (4%)
    •Headache (3%)
    •Muscle pain (2%)

  • Warnings of Evenity vs. Boniva

    Common Side Effects for
    •Risk of heart attack, stroke, or heart-related death
    •Low calcium levels (hypocalcemia)
    •Risk of problems in the jawbone (osteonecrosis of the jaw)
    •Risk of fractures in the thigh
    Common Side Effects for
    •Stomach and esophagus irritation and ulcers
    •Breakdown of the jawbone (osteonecrosis)
    •Severe bone, joint, or muscle pain
    •Leg bone fractures
    •Low calcium in the blood

  • Prices with our coupons for Evenity vs. Boniva

    Learn more about Evenity
    Learn more about Ibandronate

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