Evenity vs. Forteo for Osteoporosis: Important Differences and Potential Risks.

Evenity

(romosozumab)

Forteo

(teriparatide)

Summary for Evenity

Prescription only

Evenity (romosozumab or romosozumab-aqqg) is an injection used to treat osteoporosis (bone loss) in certain women after menopause. These women either have a high risk of fracture or can’t take other medications for bone loss. It's also used when these other medications haven’t worked well enough. Evenity (romosozumab) belongs to the drug class called sclerostin inhibitors. It works to help your bones grow and prevent bone breakdown at the same time. The injection is given once a month by a healthcare professional. Common side effects are joint pain and headache. There's also serious risks of heart attack and stroke. This medication is brand name only; there's no generic available yet.

Indications for Evenity

Treatment of osteoporosis in certain women after menopause
- With high risk of fracture
- Who can’t take other medications for bone loss
- Who tried other medications for bone loss that didn’t work

Pros and Cons for Evenity

Pros

Helps with bone growth and prevents bone loss at the same time
Given just once a month
Only need 1 year of treatment

Cons

Needs to be injected
Must go to the medical office for each injection
Bone mineral density eventually goes back to where it was before after stopping the medication

Common Side Effects for Evenity

Joint pain (up to 13%)
Headache (up to 7%)

Warnings for Evenity

Risk of heart attack, stroke, or heart-related death
Low calcium levels (hypocalcemia)
Risk of problems in the jawbone (osteonecrosis of the jaw)
Risk of fractures in the thigh

Summary for Forteo

Prescription only

Forteo (teriparatide) is used to treat osteoporosis (bone loss or weakening). It's for people who are at very high fracture risk or people who've already tried other osteoporosis medications. Forteo (teriparatide) is an injection that you give to yourself once a day. Some common side effects include general body pain and joint pain. This medication comes as a prefilled pen, but it doesn't come with pen needles. Forteo (teriparatide) is only available as a brand medication; there's no generic version yet.

Indications for Forteo

Osteoporosis in females who've gone through menopause (postmenopause)
Osteoporosis in males
Osteoporosis caused by long-term use of corticosteroids

Pros and Cons for Forteo

Pros

Can use if you're unable to take or still getting fractures with other osteoporosis medications
A first-choice option for people at very high fracture risk (have had a fracture caused by osteoporosis before or have many risk factors for fracture)
Lowers the risk for back fractures and fractures in other parts of the body (not including the hip) in postmenopausal women with osteoporosis

Cons

Not a first-choice option for most people with osteoporosis
Only available as an injection under the skin
Can only use for a total of 2 years throughout your entire life because of unclear risk for bone cancer with longer treatment

Common Side Effects for Forteo

Body pain (21%)
Joint pain (10%)
Runny nose (10%)
Nausea (9%)
Body weakness (9%)
Headache (8%)
Dizziness (8%)
High blood pressure (7%)

Warnings for Forteo

Bone cancer (osteosarcoma)
High calcium levels in the blood
Kidney stones
Low blood pressure
Higher risk of side effects from digoxin (Lanoxin)

Prices with our coupons for Evenity vs. Forteo

Evenity1 carton / 2 syringes of 105mg/1.17ml

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Teriparatide (Forteo)1 pen / 20mcg/dose

$1,035.57$3,005.60

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Evenity vs. Forteo

Evenity

Forteo

Summary for Evenity

Indications for Evenity

Pros and Cons for Evenity

Pros

Cons

Common Side Effects for Evenity

Warnings for Evenity

Summary for Forteo

Indications for Forteo

Pros and Cons for Forteo

Pros

Cons

Common Side Effects for Forteo

Warnings for Forteo

Prices with our coupons for Evenity vs. Forteo

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Evenity

Forteo

Summary for Evenity

Indications for Evenity

Pros and Cons for Evenity

Pros

Cons

Common Side Effects for Evenity

Warnings for Evenity

Summary for Forteo

Indications for Forteo

Pros and Cons for Forteo

Pros

Cons

Common Side Effects for Forteo

Warnings for Forteo