Key takeaways
Epiduo (adapalene/benzoyl peroxide) and Finacea (azelaic acid) are both topical treatments for acne, but they have some key differences. Epiduo combines a retinoid (adapalene) and a topical antibiotic (benzoyl peroxide) to treat acne by preventing pimples and reducing inflammation. It is available only by prescription and comes in two strengths, with the higher strength approved for those 12 years and older. On the other hand, Finacea contains azelaic acid, which is naturally found in grains and works by stopping the growth of acne-causing bacteria and reducing inflammation. Azelaic acid is used for both acne and rosacea and is available in cream, gel, and foam forms, with some over-the-counter options. While Epiduo is applied once daily, Finacea needs to be applied twice daily. Both medications can cause skin irritation, but Epiduo is more likely to cause sun sensitivity and bleaching of fabrics. Finacea can also lighten skin color, especially in darker skin tones.
