Skip to main content

Compare
Emtriva vs. Epzicom

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Emtriva (emtricitabine) and Epzicom (abacavir/lamivudine) are both medications used to treat HIV. They belong to the same class of medications called nucleoside reverse transcriptase inhibitors (NRTIs), which work by stopping the virus from making copies of itself. Emtriva is a single medication, while Epzicom is a combination of two medications. Emtriva is available as a capsule and an oral solution, whereas Epzicom is available as a tablet. Both medications are often used in combination with other HIV medications for treatent of HIV. Both medications are available in generic form, which can be more affordable. Both medications can cause liver problems and worsening of hepatitis B if stopped suddenly, but Epzicom also requires a genetic test to check for a risk of severe allergic reactions. Common side effects of Emtriva include nausea and fatigue, while Epzicom can cause headaches and nausea.

Emtricitabine

(Emtriva)

Get free coupons

Epzicom

 

Get free coupons

Summary for Emtriva

Prescription only

Emtricitabine (Emtriva) is a first choice HIV antiretroviral (ARV) used in combination with other HIV ARVs for the treatment and prevention of HIV. It is one of the most common HIV ARVs used around the world.

Indications for Emtriva

  • HIV treatment

Pros and Cons for Emtriva

Pros

  • Very effective against HIV, with few side effects
  • Taken only once a day with or without food
  • Available in many combination tablets with other HIV ARVs
  • Available as a capsule and oral solution
  • Can be used in pregnancy and in children right after they are born

Cons

  • Dose must be adjusted if you have kidney problems
  • Must be used in combination with other HIV ARVs
  • The oral solution is absorbed less than the capsule, so the dose is higher
  • Some people with hepatitis B virus (HBV) have worsening of the liver after stopping emtricitabine (Emtriva)
  • Requires regular labs to make sure the medication is working against HIV and to check your kidney and liver

Common Side Effects for Emtriva

  • Changes in labs (30%)
  • Nausea (9%)
  • Fatigue (9%)
  • Diarrhea (9%)
  • Dizziness (8%)
  • Flu/cold (8%)
  • Runny nose (8%)
  • Rash (7%)

Warnings for Emtriva

  • WORSENING OF HEPATITIS B
  • IMMUNE RECONSTITUTION SYNDROME
  • LIVER PROBLEMS

Summary for Epzicom

Prescription only

Epzicom is a combination medication containing two HIV antiretrovirals (ARVs), abacavir (Ziagen) and lamivudine (Epivir). It's used with other HIV ARVs for the treatment of HIV.

Indications for Epzicom

  • HIV treatment

Pros and Cons for Epzicom

Pros

  • Contains 2 first choice HIV ARV options
  • Convenient dosing (1 tablet, once a day, with or without food)
  • Same dose for everyone weighing more than 55 lbs (25 kg)
  • Contains lamivudine, which also works against hepatitis B
  • Available as a generic, which can be more affordable

Cons

  • Dose can't be adjusted so it's not recommended for people with kidney or liver problems
  • Requires a genetic test called HLA-B 5701 because the allergic reaction can be fatal
  • Not a good option for people with heart problems
  • People taking methadone might need a higher dose of methadone after starting Epzicom
  • People with hepatitis B can have worsened hepatitis B if they suddenly stop taking Epzicom

Common Side Effects for Epzicom

  • Headache (7%)
  • Tiredness and fatigue (6%)
  • Dizziness (6%)
  • Nausea (5%)
  • Diarrhea (5%)
  • Rash (5%)
  • Fever (5%)

Warnings for Epzicom

  • SEVERE ALLERGIC REACTION
  • WORSENING OF HEPATITIS B
  • LIVER PROBLEMS
  • IMMUNE RECONSTITUTION SYNDROME
  • HEART ATTACK

Prices with our coupons for Emtriva vs. Epzicom

Price Card Drug Icon
Emtricitabine30 capsules / 200mg
$152.24-
Get free coupons
More Information
Price Card Drug Icon
Abacavir/Lamivudine90 tablets / 600mg/300mg of
$108.53$2,921.98
Get free coupons
More Information

Browse medications by letter

Show All

Browse prescription and over-the-counter medications from A to Z, compare drug prices, and start saving.