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Dayquil vs. Sudafed PE

Dayquil Cold and Flu is a combination of three active ingredients: acetaminophen (an analgesic), dextromethorphan (a cough suppressant), and phenylephrine (a decongestant). Dayquil Cold and Flu helps treat symptoms from the common cold and flu in adults and children. It can relieve stuffy nose, cough, sore throat, headache, aches, and fever. Besides Dayquil Cold and Flu, this medication is available under many other brand names and as a generic. It's available as pills and a liquid that's typically taken every 4 hours. Side effects aren't common but can include stomach upset and nervousness.

• Short-term relief of symptoms from the common cold and flu:
  • Minor aches and pains
  • Headache
  • Stuffy nose (nasal congestion)
  • Cough
  • Sore throat
  • Fever

• Stomach upset
• Nervousness or anxiety

• Liver damage
• Allergic skin reactions
• Serotonin syndrome
• Accidentally taking too much medication
• Worsening of certain medical conditions

Phenylephrine (Sudafed PE) is a decongestant used to treat nasal and sinus congestion from allergies and the common cold. It's available over the counter as tablets and a liquid solution. Phenylephrine (Sudafed PE) isn't a first-choice option for people who are pregnant or breastfeeding because there's a chance that it can affect the growing baby and the mother's milk supply. Side effects of phenylephrine (Sudafed PE) are typically mild and can include feeling anxious, headache, and nausea.

• Short-term relief of nasal and sinus congestion and pressure

• Feeling anxious
• Headache
• Nausea

• High heart rate and blood pressure
• Accidental overdose
• Worsening of medical conditions