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Compare Climara vs. Climara Pro

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Climara (estradiol patch)
    Climara pro (estradiol / levonorgestrel)
  • Climara (estradiol patch)
    Climara pro (estradiol / levonorgestrel)

  • Summary of Climara vs. Climara Pro

    Summary for Estrogen replacement
    Prescription only

    The Climara (estradiol patch) is a once-weekly hormonal patch that relieves menopause symptoms and treats low estrogen levels. It can also help prevent bone loss (osteoporosis) in people who have gone through menopause. The patch is a type of hormone replacement therapy (HRT) and typically has fewer side effects than oral estrogen pills. You'll apply one patch to the skin of your lower stomach or the upper buttocks once a week. Potential side effects of this hormone patch include breast pain, headaches, and stomach pain.

    Summary for Estrogen replacement / Progestin
    Prescription only

    Climara Pro is a patch that's applied to the skin once a week. It's approved to prevent osteoporosis in people who've gone through menopause. This medication can also treat symptoms like hot flashes and night sweats from menopause. The patch is a hormone replacement therapy; it contains the hormones estradiol and levonorgestrel. Side effects include irregular vaginal bleeding or spotting, breast pain, and skin irritation where the patch is applied.

  • Indications of Climara vs. Climara Pro

    Indications for
    •Hot flashes, night sweats, and flushes caused by menopause
    •Vaginal dryness and irritation caused by menopause
    •Low estrogen levels due to certain conditions
    •Prevention of osteoporosis after menopause
    Indications for
    •Treatment of moderate-to-severe symptoms of menopause (e.g., hot flashes, night sweats) for people with a healthy uterus
    •Prevention of osteoporosis for people who've gone through menopause with a healthy uterus

  • Pros and Cons of Climara vs. Climara Pro

    Pros and Const for Estrogen replacement
    Pros
    •Relieves multiple menopause symptoms
    •Only need to apply once a week
    •Might have fewer side effects than oral estrogen pills
    •Available in different strengths, allowing you to customize your dose
    Cons
    •Commonly causes breast pain, headaches, and stomach pain
    •Can cause skin irritation, redness, and itchiness at the patch site
    •Raises your risk of certain cancers, blood clots, and strokes
    •Might need to take it with another hormone called progestin if you have a healthy uterus
    Pros and Const for Estrogen replacement / Progestin
    Pros
    •Comes as a patch, so it might be a good option for people who have trouble swallowing pills
    •Applied once every week
    •Might have fewer side effects than estrogen pills
    Cons
    •Can fall off if it gets too wet
    •No lower-cost generic available; brand name only
    •Not a first-choice option for preventing osteoporosis for people who've gone through menopause

  • Common Side Effects of Climara vs. Climara Pro

    Common Side Effects for
    •Breast pain (up to 29%)
    •Headache (up to 18%)
    •Upper respiratory tract infection (up to 17%)
    •Stomach pain (up to 16%)
    •Swelling (up to 13%)
    •Back and body pain (up to 11%)
    •Depression (up to 8%)
    •Vaginal discharge (up to 7%)
    •Excessive gas (up to 7%)
    •Itching (up to 6%)
    •Nausea (up to 6%)
    Common Side Effects for
    •Application site reaction (e.g., skin irritation; 41%)
    •Vaginal bleeding or spotting (37%)
    •Breast pain (19%)
    •Upper respiratory infection (13%)
    •Depression (6%)
    •Back pain (6%)
    •General pain (5%)
    •Headache (5%)
    •Flu-like symptoms (5%)

  • Warnings of Climara vs. Climara Pro

    Common Side Effects for
    •Blood clots and related complications (e.g., heart attack, stroke)
    •Uterine (endometrial) cancer
    •Breast cancer
    •Ovarian cancer
    •Dementia
    •Gallbladder and liver problems
    •Vision problems
    •High triglycerides
    •Low thyroid hormone levels (hypothyroidism)
    •Fluid Retention
    •Worsening of other health conditions
    Common Side Effects for
    •Blood clots and related complications (e.g., heart attacks, strokes)
    •Breast cancer
    •Uterine or endometrial cancer
    •Ovarian cancer
    •Risk for dementia
    •Gallbladder problems and jaundice
    •Changes in calcium levels in the blood
    •Changes in vision
    •High triglyceride (fat) levels
    •Low thyroid hormone levels in people who take thyroid hormone replacement therapy
    •Buildup of fluids in your body (fluid retention)

  • Prices with our coupons for Climara vs. Climara Pro

    Learn more about Climara
    Learn more about Climara pro

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