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Ciprodex vs. Otovel

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Ciprodex (ciprofloxacin/dexamethasone) and Otovel (ciprofloxacin/fluocinolone) are both ear drop medications used to treat ear infections in children aged 6 months and older. Ciprodex can treat both middle ear infections with ear tubes and outer ear infections (swimmer's ear), while Otovel is only for middle ear infections with ear tubes. Ciprodex combines ciprofloxacin, an antibiotic, with dexamethasone, a corticosteroid, whereas Otovel combines ciprofloxacin with fluocinolone, another corticosteroid. Ciprodex is available as a lower-cost generic, while Otovel comes in convenient, single-use vials but can be more expensive. Both medications need to be warmed in your hands before use to prevent dizziness and are used twice a day for 7 days. Common side effects for Ciprodex include ear discomfort and pain, while Otovel commonly causes ear drainage. Both medications carry risks of serious allergic reactions and should not be used for viral or fungal ear infections.

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Otovel

Ciprodex

(ciprofloxacin / dexamethasone)

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Otovel

(ciprofloxacin / fluocinolone)

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Summary for Ciprodex

Prescription only

Ciprodex is an ear drop suspension that contains ciprofloxacin (a fluoroquinolone antibiotic) and dexamethasone (a corticosteroid). It's used to treat middle and outer ear infections in people ages 6 years and older. The dosage is 4 drops twice a day, typically for 7 days. Side effects aren't common, but include ear discomfort, ear pain, and changes in taste. It's available as both a brand name (Ciprodex) and generic.

Indications for Ciprodex

  • Middle ear infections (otitis media) in children ages 6 months and older with surgically-placed ear tubes (tympanostomy tubes)
  • Outer ear canal infections (swimmer's ear or otitis externa) in people 6 months and older

Pros and Cons for Ciprodex

Pros

  • Combines two medications into a single ear drop
  • Generally only needs to be used for 7 days
  • Can be used in children as young as 6 months old

Cons

  • Need to use twice a day
  • Can be difficult for some people to administer correctly
  • Can only treat ear infections caused by bacteria, not infections caused by fungi or viruses

Common Side Effects for Ciprodex

  • Ear discomfort (3%)
  • Ear pain (2%)
  • Itchy ear (2%)

Warnings for Ciprodex

  • Severe allergic reactions
  • Development of new infection
  • Use only in the ear

Summary for Otovel

Prescription only

Otovel (ciprofloxacin / fluocinolone) is a combination antibiotic and steroid medication that treats ear infections in children aged 6 months and older with surgically placed ear tubes (tympanostomy tubes). It's an ear drop that comes in convenient, single-use vials.

Indications for Otovel

  • Middle ear infections in children with ear tubes

Pros and Cons for Otovel

Pros

  • Starts working within a few days
  • Comes as a ready-to-use vial
  • A good option for children who have ear tubes

Cons

  • Needs to be warmed in your hands before giving to prevent dizziness
  • Must be given twice a day
  • Can be expensive

Common Side Effects for Otovel

  • Drainage from the ear (5%)

Warnings for Otovel

  • Allergic reactions
  • New infection after long-term use
  • Continued or recurring ear drainage

Prices with our coupons for Ciprodex vs. Otovel

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Ciprofloxacin/Dexamethasone1 ear dropper / 7.5ml of 0.3%/0.1%
$65.04$211.07
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Otovel14 vials / 0.25ml of 0.3%/0.025%
$333.25$362.78
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