Key takeaways
Cefuroxime (generic name for the discontinued brand Ceftin) and cefdinir (generic name for the discontinued brand Omnicef) are both cephalosporin antibiotics used to treat bacterial infections. They share some common uses, such as treating sinus infections, ear infections, and strep throat. However, cefdinir is not FDA-approved for urinary tract infections (UTIs), though it is sometimes used off-label for this purpose, especially in children. Cefuroxime is available as tablets and injections, while cefdinir comes in capsules and an oral suspension. Cefuroxime is typically taken every 12 hours, whereas cefdinir can be taken once or twice a day, depending on the infection. Both medications can cause side effects like diarrhea and nausea, but cefdinir has a higher reported rate of diarrhea. You should avoid certain medications with both antibiotics; for cefuroxime, avoid heartburn medications, and for cefdinir, avoid antacids and iron supplements. Both medications are generally safe during pregnancy, but you should discuss with your healthcare provider.
