Key takeaways
Cefpodoxime and Teflaro (ceftaroline) are both cephalosporin antibiotics, but they have some key differences. Cefpodoxime is a third-generation cephalosporin available as a generic oral medication, while Teflaro is a fifth-generation cephalosporin given as an intravenous (IV) infusion. Cefpodoxime treats a wide range of infections, including strep throat, pneumonia, and UTIs, and is taken twice a day. Teflaro, on the other hand, is used mainly for serious skin infections and pneumonia, especially those caused by resistant bacteria like MRSA, and is administered every 8 to 12 hours. While both medications can cause side effects like diarrhea and nausea, Teflaro can also lead to nervous system issues such as confusion and seizures, particularly in people with kidney problems. Additionally, Teflaro is only available as a brand-name medication, whereas cefpodoxime is available in a lower-cost generic form.
