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Vantin vs. Teflaro

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Cefpodoxime and Teflaro (ceftaroline) are both cephalosporin antibiotics, but they have some key differences. Cefpodoxime is a third-generation cephalosporin available as a generic oral medication, while Teflaro is a fifth-generation cephalosporin given as an intravenous (IV) infusion. Cefpodoxime treats a wide range of infections, including strep throat, pneumonia, and UTIs, and is taken twice a day. Teflaro, on the other hand, is used mainly for serious skin infections and pneumonia, especially those caused by resistant bacteria like MRSA, and is administered every 8 to 12 hours. While both medications can cause side effects like diarrhea and nausea, Teflaro can also lead to nervous system issues such as confusion and seizures, particularly in people with kidney problems. Additionally, Teflaro is only available as a brand-name medication, whereas cefpodoxime is available in a lower-cost generic form.

Cefpodoxime

 

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Ceftaroline

(Teflaro)

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Summary for Vantin

Prescription only

Cefpodoxime is a cephalosporin antibiotic. It's used to treat several types of bacterial infections, such as urinary tract infection (UTI), pneumonia, and strep throat, in adults and children. The brand-name product Vantin is discontinued, but the antibiotic is still available as a lower-cost generic tablet and suspension. The dosage depends on your age and the type of infection you have, but cefpodoxime is typically taken twice per day by mouth. Side effects include diarrhea and nausea.

Indications for Vantin

Pros and Cons for Vantin

Pros

  • Treats many types of bacterial infections throughout the body
  • Can use to treat infections in both children and adults
  • Available as a tablet and liquid suspension
  • Available as a lower-cost generic

Cons

  • Need to take twice per day to treat most infections
  • Might not be able to take if you have a severe allergy to penicillins or other cephalosporin antibiotics
  • Not recommended for the cold or flu, since they're not caused by a bacterial infection

Common Side Effects for Vantin

  • Diaper rash or fungal skin rash in children (up to 9%)
  • Diarrhea (up to 7% in adults; up to 13% in children under 2 years old)
  • Nausea (3%)
  • Vomiting (2%)

Warnings for Vantin

  • Severe allergic reaction
  • Diarrhea from Clostridioides difficile infection
  • Possible development of drug-resistant bacteria

Summary for Teflaro

Prescription only

Ceftaroline, also known by its brand name Teflaro, is a fifth-generation cephalosporin antibiotic that's used to treat pneumonia and skin infections. It's usually used for people who might have an infection from resistant bacteria, such as MRSA. Ceftaroline (Teflaro) is administered as an intravenous (IV) infusion. Side effects can include diarrhea, nausea, and rash. Ceftaroline (Teflaro) is similar to penicillin, so it might not be a good choice for people with a penicillin allergy.

Indications for Teflaro

Pros and Cons for Teflaro

Pros

  • Works well at treating serious bacterial infections of the skin and lungs
  • Can use to treat adults and children of all ages
  • Doesn't interact with other medications
  • Can fight against resistant bacteria like MRSA

Cons

  • Needs to be given as an IV infusion by a healthcare provider
  • Only approved for skin infections and certain types of pneumonia
  • Given every 8 to 12 hours
  • Available as a brand-name medication only

Common Side Effects for Teflaro

Adults:

  • Diarrhea (5%)
  • Nausea (4%)
  • Rash (3%)

Children:

  • Diarrhea (8%)
  • Rash (7%)
  • Vomiting (5%)
  • Nausea (3%)
  • Fever (3%)

Warnings for Teflaro

  • Allergic reactions
  • Diarrhea from Clostridioides difficile infection
  • Nervous system side effects
  • Development of drug-resistant bacteria

Prices with our coupons for Vantin vs. Teflaro

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Cefpodoxime14 tablets / 200mg
$29.65$84.66
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Teflaro14 vials / 600mg
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