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Teflaro vs. Omnicef

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Teflaro (ceftaroline) and Omnicef (cefdinir) are both cephalosporin antibiotics, but they have some key differences. Teflaro is a fifth-generation cephalosporin given as an intravenous (IV) infusion, while Omnicef is taken orally as capsules or a liquid suspension. Teflaro is used to treat pneumonia and skin infections, including those caused by resistant bacteria like MRSA, whereas Omnicef treats a broader range of infections such as pneumonia, sinus infections, strep throat, and ear infections in children. Teflaro is only available as a brand-name medication, while Omnicef is available in generic form. Teflaro needs to be administered by a healthcare provider every 8 to 12 hours, whereas Omnicef can be taken once or twice a day at home. Both medications can cause side effects like diarrhea and rash, but Teflaro can also lead to serious nervous system side effects, especially in people with kidney problems.

Ceftaroline

(Teflaro)

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Cefdinir

 

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Summary for Teflaro

Prescription only

Ceftaroline, also known by its brand name Teflaro, is a fifth-generation cephalosporin antibiotic that's used to treat pneumonia and skin infections. It's usually used for people who might have an infection from resistant bacteria, such as MRSA. Ceftaroline (Teflaro) is administered as an intravenous (IV) infusion. Side effects can include diarrhea, nausea, and rash. Ceftaroline (Teflaro) is similar to penicillin, so it might not be a good choice for people with a penicillin allergy.

Indications for Teflaro

Pros and Cons for Teflaro

Pros

  • Works well at treating serious bacterial infections of the skin and lungs
  • Can use to treat adults and children of all ages
  • Doesn't interact with other medications
  • Can fight against resistant bacteria like MRSA

Cons

  • Needs to be given as an IV infusion by a healthcare provider
  • Only approved for skin infections and certain types of pneumonia
  • Given every 8 to 12 hours
  • Available as a brand-name medication only

Common Side Effects for Teflaro

Adults:

  • Diarrhea (5%)
  • Nausea (4%)
  • Rash (3%)

Children:

  • Diarrhea (8%)
  • Rash (7%)
  • Vomiting (5%)
  • Nausea (3%)
  • Fever (3%)

Warnings for Teflaro

  • Allergic reactions
  • Diarrhea from Clostridioides difficile infection
  • Nervous system side effects
  • Development of drug-resistant bacteria

Summary for Omnicef

Prescription only

Cefdinir, also known by its brand name Omnicef, is a cephalosporin antibiotic that can treat several types of bacterial infections, such as pneumonia, sinus infections, and ear infections. Although the brand name is no longer available, its generic can still be prescribed for adults and children. Cefdinir comes as capsules and a suspension that are taken once or twice per day by mouth. Side effects can include diarrhea, nausea, and rash.

Indications for Omnicef

Pros and Cons for Omnicef

Pros

  • Available as a capsule and oral suspension
  • Can be used for children and adults
  • Might be able to take once per day, depending on the infection
  • Can keep oral suspension at room temperature for up to 10 days

Cons

  • Might not be able to take this antibiotic if you've had a severe allergic reaction to penicillins or other cephalosporin antibiotics
  • Must separate when you take cefdinir and antacids or iron supplements by at least 2 hours
  • Oral suspension contains sugar, so people with diabetes might have higher blood sugar levels while they're taking the antibiotic
  • Not recommended for the cold or flu, since they're not caused by a bacterial infection

Common Side Effects for Omnicef

  • Diarrhea (up to 15%)

Warnings for Omnicef

  • Severe allergic reactions
  • Diarrhea from Clostridioides difficile infection
  • Possible development of drug-resistant bacteria

Prices with our coupons for Teflaro vs. Omnicef

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Teflaro14 vials / 600mg
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Cefdinir20 capsules / 300mg
$20.88$33.02
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