Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Teflaro vs. Omnicef

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Teflaro (ceftaroline) and Omnicef (cefdinir) are both cephalosporin antibiotics, but they have some key differences. Teflaro is a fifth-generation cephalosporin given as an intravenous (IV) infusion, while Omnicef is taken orally as capsules or a liquid suspension. Teflaro is used to treat pneumonia and skin infections, including those caused by resistant bacteria like MRSA, whereas Omnicef treats a broader range of infections such as pneumonia, sinus infections, strep throat, and ear infections in children. Teflaro is only available as a brand-name medication, while Omnicef is available in generic form. Teflaro needs to be administered by a healthcare provider every 8 to 12 hours, whereas Omnicef can be taken once or twice a day at home. Both medications can cause side effects like diarrhea and rash, but Teflaro can also lead to serious nervous system side effects, especially in people with kidney problems.

  • Ceftaroline (Teflaro)
    Cefdinir
  • Ceftaroline (Teflaro)
    Cefdinir

  • Summary of Teflaro vs. Omnicef

    Summary for Cephalosporin antibiotic
    Prescription only

    Ceftaroline, also known by its brand name Teflaro, is a fifth-generation cephalosporin antibiotic that's used to treat pneumonia and skin infections. It's usually used for people who might have an infection from resistant bacteria, such as MRSA. Ceftaroline (Teflaro) is administered as an intravenous (IV) infusion. Side effects can include diarrhea, nausea, and rash. Ceftaroline (Teflaro) is similar to penicillin, so it might not be a good choice for people with a penicillin allergy.

    Summary for Cephalosporin antibiotic
    Prescription only

    Cefdinir, also known by its brand name Omnicef, is a cephalosporin antibiotic that can treat several types of bacterial infections, such as pneumonia, sinus infections, and ear infections. Although the brand name is no longer available, its generic can still be prescribed for adults and children. Cefdinir comes as capsules and a suspension that are taken once or twice per day by mouth. Side effects can include diarrhea, nausea, and rash.

  • Indications of Teflaro vs. Omnicef

    Indications for
    •Pneumonia
    •Bacterial skin infections (e.g., cellulitis)
    Indications for
    •Pneumonia
    •Lung infections related to long-term bronchitis
    •Sinus infections
    •Strep throat
    •Tonsil infections
    •Skin infections
    •Ear infections - for children only

  • Pros and Cons of Teflaro vs. Omnicef

    Pros and Const for Cephalosporin antibiotic
    Pros
    •Works well at treating serious bacterial infections of the skin and lungs
    •Can use to treat adults and children of all ages
    •Doesn't interact with other medications
    •Can fight against resistant bacteria like MRSA
    Cons
    •Needs to be given as an IV infusion by a healthcare provider
    •Only approved for skin infections and certain types of pneumonia
    •Given every 8 to 12 hours
    •Available as a brand-name medication only
    Pros and Const for Cephalosporin antibiotic
    Pros
    •Available as a capsule and oral suspension
    •Can be used for children and adults
    •Might be able to take once per day, depending on the infection
    •Can keep oral suspension at room temperature for up to 10 days
    Cons
    •Might not be able to take this antibiotic if you've had a severe allergic reaction to penicillins or other cephalosporin antibiotics
    •Must separate when you take cefdinir and antacids or iron supplements by at least 2 hours
    •Oral suspension contains sugar, so people with diabetes might have higher blood sugar levels while they're taking the antibiotic
    •Not recommended for the cold or flu, since they're not caused by a bacterial infection

  • Common Side Effects of Teflaro vs. Omnicef

    Common Side Effects for

    Adults:

    •Diarrhea (5%)
    •Nausea (4%)
    •Rash (3%)

    Children:

    •Diarrhea (8%)
    •Rash (7%)
    •Vomiting (5%)
    •Nausea (3%)
    •Fever (3%)
    Common Side Effects for
    •Diarrhea (up to 15%)

  • Warnings of Teflaro vs. Omnicef

    Common Side Effects for
    •Allergic reactions
    •Diarrhea from Clostridioides difficile infection
    •Nervous system side effects
    •Development of drug-resistant bacteria
    Common Side Effects for
    •Severe allergic reactions
    •Diarrhea from Clostridioides difficile infection
    •Possible development of drug-resistant bacteria

  • Prices with our coupons for Teflaro vs. Omnicef

    Learn more about Ceftaroline
    Learn more about Cefdinir

Compare other Skin Infection and Pneumonia drugs

Teflaro vs CedaxTeflaro vs CeftinTeflaro vs OmnicefVantin vs TeflaroAugmentin vs BactrimBactrim vs AmoxicillinBactrim vs CefdinirBactrim vs CiproBactrim vs ClindamycinBactrim vs KeflexCeftin vs CefdinirCeftin vs KeflexDoxycycline vs BactrimFlagyl vs BactrimKeflex vs CedaxLevaquin vs BactrimMacrobid vs BactrimMacrodantin vs BactrimMalarone vs BactrimMinocycline vs BactrimNitrofurantoin vs BactrimOmnicef vs CedaxRocephin vs CeftinVantin vs AugmentinVantin vs BactrimVantin vs CedaxVantin vs CeftinVantin vs CiproVantin vs PenicillinXenleta vs Ceftin
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.