Key takeaways
Ceftriaxone (generic name) and Cefepime (brand name Maxipime) are both cephalosporin antibiotics used to treat bacterial infections, but they have some differences. Ceftriaxone is typically given once a day and can be administered either intravenously or intramuscularly, making it versatile for various settings, including home use. In contrast, Cefepime is usually given every 8 to 12 hours and is primarily administered intravenously, though it can be given intramuscularly for certain urinary tract infections. Cefepime is a fourth-generation cephalosporin, which means it can treat some infections caused by resistant bacteria, including Pseudomonas aeruginosa, whereas Ceftriaxone is not as effective against resistant bacteria. Both medications can cause similar side effects, such as diarrhea and nervous system issues, but Cefepime may require more frequent dosing and closer monitoring, especially in people with kidney problems. Additionally, Ceftriaxone is generally considered safe during pregnancy until close to delivery, while Cefepime's safety in pregnancy isn't specified.
