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Compare Rocephin vs. Maxipime

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Ceftriaxone (generic name) and Cefepime (brand name Maxipime) are both cephalosporin antibiotics used to treat bacterial infections, but they have some differences. Ceftriaxone is typically given once a day and can be administered either intravenously or intramuscularly, making it versatile for various settings, including home use. In contrast, Cefepime is usually given every 8 to 12 hours and is primarily administered intravenously, though it can be given intramuscularly for certain urinary tract infections. Cefepime is a fourth-generation cephalosporin, which means it can treat some infections caused by resistant bacteria, including Pseudomonas aeruginosa, whereas Ceftriaxone is not as effective against resistant bacteria. Both medications can cause similar side effects, such as diarrhea and nervous system issues, but Cefepime may require more frequent dosing and closer monitoring, especially in people with kidney problems. Additionally, Ceftriaxone is generally considered safe during pregnancy until close to delivery, while Cefepime's safety in pregnancy isn't specified.

  • Ceftriaxone
    Cefepime (Maxipime)
  • Ceftriaxone
    Cefepime (Maxipime)

  • Summary of Rocephin vs. Maxipime

    Summary for Cephalosporin antibiotic
    Prescription only

    Ceftriaxone is one of the most commonly used antibiotics because of its low risk for side effects and its ability to treat several types of bacterial infections. Ceftriaxone is an injection given either into the veins or into the muscle, so it's used most often in the hospital or a clinic setting (e.g., nursing home, provider's office). But it can also be used at home in certain situations. The dosage depends on the type and severity of your infection, but it's usually given once per day. If you have a penicillin allergy, you might still be able to receive ceftriaxone depending on your reaction to penicillin.

    Summary for Cephalosporin antibiotic
    Prescription only

    Cefepime (also known by its brand name, Maxipime) is an antibiotic that treats a wide range of bacterial infections, including pneumonia, skin infections, stomach infections, and urinary tract infections (UTIs). It belongs to the cephalosporin drug class (fourth generation). Cefepime (Maxipime) is typically given as an injection through the veins (intravenous or IV). It can also be given as an injection into the muscle for certain UTIs. Your provider will decide on the dose depending on the type and severity of the infection and your kidney health. Some side effects include reactions at the injection site, like pain and inflammation.

  • Indications of Rocephin vs. Maxipime

    Indications for
    •Lower respiratory tract infections (e.g., pneumonia, bronchitis)
    •Ear infections
    •Stomach infections
    •Urinary tract infections (UTIs)
    •Skin infections (e.g., cellulitis)
    •Bone and joint infections
    •Bloodstream infections
    •Meningitis
    •Gonorrhea
    •Pelvic inflammatory disease (PID)
    •Preventing infection from surgery
    Indications for
    •Pneumonia
    •Urinary tract infections (UTIs)
    •Skin infections (e.g., cellulitis)
    •Stomach infections - add-on therapy to metronidazole (Flagyl)
    •Treatment of possible infections in people with febrile neutropenia

  • Pros and Cons of Rocephin vs. Maxipime

    Pros and Const for Cephalosporin antibiotic
    Pros
    •Can treat many different types of infections
    •Can use in people with kidney problems
    •Can use in children
    •Typically given once per day
    Cons
    •Must be given by an injection into the veins or into the muscle
    •Sometimes requires twice-daily dosing for more severe infections
    •Not a good choice for treating infections caused by resistant bacteria
    •Might not be the best choice if you've had an allergic reaction to penicillins or other cephalosporin antibiotics
    Pros and Const for Cephalosporin antibiotic
    Pros
    •Covers many types of bacteria
    •Can treat some infections caused by certain resistant bacteria
    •Gets into the body quickly to start treating infections
    •Can use in children as young as 2 months of age
    Cons
    •Must be given as an injection into the veins (or into the muscle for certain UTIs)
    •Might need to be given as often as every 8 hours
    •Can cause nervous system side effects
    •Might not be the best choice if you've had an allergic reaction to penicillins or other cephalosporin antibiotics

  • Common Side Effects of Rocephin vs. Maxipime

    Common Side Effects for
    •Side effects aren't common. See Other Side Effects.
    Common Side Effects for
    •Side effects aren't common. See Other Side Effects.

  • Warnings of Rocephin vs. Maxipime

    Common Side Effects for
    •Allergic reactions
    •Avoid administration with calcium-containing medications
    •Nervous system side effects
    •Diarrhea from Clostridioides difficile infection
    •Low red blood cell count (hemolytic anemia)
    •Development of drug-resistant bacteria
    Common Side Effects for
    •Allergic reactions
    •Nervous system side effects
    •Diarrhea from Clostridioides difficile infection
    •Development of drug-resistant bacteria

  • Prices with our coupons for Rocephin vs. Maxipime

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