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Cefdinir vs. Vibramycin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Cefdinir (Omnicef) and doxycycline hyclate (Vibramycin, Doryx) are both antibiotics used to treat bacterial infections, including sinus infections. However, they belong to different medication classes. Cefdinir is a cephalosporin antibiotic, while doxycycline hyclate is a tetracycline antibiotic. Cefdinir is available as capsules and oral suspension, typically taken once or twice a day, and is often used off-label for urinary tract infections (UTIs) in children. Doxycycline hyclate comes in capsules, tablets, and liquid syrup, and is also used for conditions like acne and sexually transmitted infections (STIs). It is taken once or twice daily. Cefdinir can cause side effects like diarrhea and rash, and it interacts with antacids and iron supplements. Doxycycline hyclate may cause stomach upset and sun sensitivity, and it interacts with blood thinners and birth control pills. While cefdinir is generally safe during pregnancy, doxycycline hyclate is not recommended for pregnant women or young children due to risks of tooth discoloration and bone growth issues.

Cefdinir

 

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doxycycline hyclate

 

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Summary for Cefdinir

Prescription only

Cefdinir, also known by its brand name Omnicef, is a cephalosporin antibiotic that can treat several types of bacterial infections, such as pneumonia, sinus infections, and ear infections. Although the brand name is no longer available, its generic can still be prescribed for adults and children. Cefdinir comes as capsules and a suspension that are taken once or twice per day by mouth. Side effects can include diarrhea, nausea, and rash.

Indications for Cefdinir

Pros and Cons for Cefdinir

Pros

  • Available as a capsule and oral suspension
  • Can be used for children and adults
  • Might be able to take once per day, depending on the infection
  • Can keep oral suspension at room temperature for up to 10 days

Cons

  • Might not be able to take this antibiotic if you've had a severe allergic reaction to penicillins or other cephalosporin antibiotics
  • Must separate when you take cefdinir and antacids or iron supplements by at least 2 hours
  • Oral suspension contains sugar, so people with diabetes might have higher blood sugar levels while they're taking the antibiotic
  • Not recommended for the cold or flu, since they're not caused by a bacterial infection

Common Side Effects for Cefdinir

  • Diarrhea (up to 15%)

Warnings for Cefdinir

  • Severe allergic reactions
  • Diarrhea from Clostridioides difficile infection
  • Possible development of drug-resistant bacteria

Summary for Vibramycin

Prescription only

Doxycycline hyclate is an antibiotic that treats many conditions, including acne, chlamydia, sinus infection, and urinary tract infection (UTI). It's taken by mouth, typically once or twice daily. It comes as capsules, tablets, and a liquid syrup. Side effects of doxycycline hyclate include stomach upset, nausea, and vomiting.

Indications for Vibramycin

Doxycycline hyclate is used to prevent malaria due to the parasite Plasmodium falciparum and to treat many different infections caused by bacteria. Some examples include:

  • Respiratory tract infections, including in the nose, throat, and lungs
  • Infections caused by ticks, mites, or fleas (Rocky Mountain spotted fever or typhus fever)
  • Sexually-transmitted infections (STIs) like chlamydia, gonorrhea, chancroid, and syphilis
  • Lyme disease
  • Urinary tract infections (UTIs)
  • Severe acne
  • Anthrax
  • Plague
  • Cholera

Pros and Cons for Vibramycin

Pros

  • Good alternative for some infections if you're allergic to penicillins
  • Treats many different infections, including severe acne and sexually transmitted infections (STIs) like chlamydia
  • Available as a liquid for those who have trouble swallowing pills
  • Likely safe for people who have kidney problems

Cons

  • Can raise your risk of sunburns
  • Can sometimes cause stomach discomfort or stomach upset
  • Interacts with blood thinners and birth control pills
  • Not safe for young children or pregnant females

Common Side Effects for Vibramycin

  • Stomach upset
  • Nausea
  • Vomiting
  • Loss of appetite
  • Sunburn

Warnings for Vibramycin

  • Permanent tooth discoloration
  • Severe diarrhea
  • Severe skin reactions
  • High pressure in the brain (intracranial hypertension or pseudotumor cerebri)
  • Harm to unborn and young babies
  • Sunburn
  • Damage to the esophagus
  • New infections
  • Drug-resistant bacteria

Prices with our coupons for Cefdinir vs. Vibramycin

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Cefdinir20 capsules / 300mg
$19.90$68.56
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Doxycycline Hyclate14 capsules / 100mg
$10.44$11.30
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