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Benzocaine vs. Lidoderm

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Benzocaine topical and lidocaine viscous (Xylocaine) are both local anesthetics used to relieve pain, but they have important differences. Benzocaine topical, available over-the-counter, is used for temporary relief of pain and itching from minor skin irritations like burns, cuts, and insect bites. It comes in various forms such as creams, gels, and sprays. Lidocaine viscous, on the other hand, is prescription-only and is used to numb painful sores in the mouth and throat, as well as to prevent gagging during dental procedures. It is typically swished and spit or swallowed. Both medications can cause a rare but serious condition called methemoglobinemia. Common side effects of benzocaine include mild burning or stinging, whereas lidocaine can cause dizziness, drowsiness, and blurred vision. It's important to follow dosing instructions carefully for both medications to avoid serious side effects.

benzocaine topical

 

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Lidocaine 5% patch

(Lidoderm)

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Summary for Benzocaine

Over-the-counter

Benzocaine topical is a local anesthetic. It temporarily eases minor skin irritations and pain by blocking pain signals. Benzocaine topical is applied to the skin, typically 3 to 4 times a day; most products can be used by adults and children ages 2 years and older. You can find it over-the-counter (OTC) in many dosage forms, including spray, gel, and cream. Benzocaine topical might cause some mild burning or stinging as side effects.

Indications for Benzocaine

Temporary relief of pain and itching from minor skin irritations, including:

Pros and Cons for Benzocaine

Pros

  • Available over the counter as a lower-cost generic
  • Can be applied directly to the painful area
  • Comes in many dosage forms (e.g., cream, gel, ointment, spray, swab)
  • Can be used as needed
  • Can be used in children as young as 2 years old

Cons

  • Not recommended for use over large areas of injured or blistered skin because of higher risk of side effects
  • Can cause irritation if it makes contact with the eyes
  • Generally not recommended for use for longer than 1 week, unless directed by your provider
  • Young children and older adults have a higher risk of a serious blood condition from this medication.

Common Side Effects for Benzocaine

Warnings for Benzocaine

  • Blood problems (methemoglobinemia)
  • Serious allergic reaction to topical pain medications

Summary for Lidoderm

Prescription only

Lidocaine 5% patch (Lidoderm) is a prescription medication used to relieve nerve pain caused by a shingles infection, also called postherpetic neuralgia (PHN). It's a local anesthetic that works by numbing your nerves to help reduce pain. You apply the patch directly to the painful area of your skin once a day, and it can be worn for up to 12 hours in a 24-hour period. Common side effects include temporary skin irritation, redness, and a mild burning sensation where the patch is applied.

Indications for Lidoderm

Pros and Cons for Lidoderm

Pros

  • Works directly on the skin
  • Generally well-tolerated with few side effects
  • Can cut patches to fit the area of pain

Cons

  • Commonly causes skin irritation
  • Must avoid contact with water wearing the patch
  • Might interact with many medications

Common Side Effects for Lidoderm

  • Blisters
  • Bruising
  • Burning sensation
  • Changes in skin color
  • Rash or redness
  • Swelling
  • Peeling or flaking skin
  • Itching
  • Small bumps or spots
  • Tiny red or purple dots under the skin
  • Tingling or numbness in the area

Warnings for Lidoderm

  • Blood problem (methemoglobinemia)
  • Absorbing too much medication
  • Accidental poisoning in children or pets

Prices with our coupons for Benzocaine vs. Lidoderm

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Benzocaine1 tube / 28g of 20%
$7.85-
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Lidocaine30 patches / 5%
$60.19$128.58
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