Key takeaways
Azelastine and mometasone are both nasal sprays used to treat allergy symptoms, but they belong to different medication classes. Azelastine is an antihistamine that helps relieve nasal symptoms like runny or stuffy nose by blocking histamine, while mometasone is a corticosteroid that reduces inflammation in the nose. Azelastine is available as a prescription-only generic nasal spray in two strengths (0.1% and 0.15%), and the 0.15% strength is also available over the counter under the brand name Astepro Allergy. Mometasone, on the other hand, is available both as a prescription and over-the-counter under the brand name Nasonex 24HR Allergy. Azelastine is typically used twice a day, while mometasone is usually taken once daily. Common side effects of azelastine include a bitter taste, nosebleeds and sleepiness, whereas mometasone can cause headaches and nosebleeds. Unlike azelastine, mometasone does not cause drowsiness, but it may lead to more serious side effects like vision changes and slowed wound healing with long-term use.
