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Adderall vs. Concerta

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Adderall (mixed amphetamine salts) and Concerta (methylphenidate extended-release) are both stimulant medications used to treat ADHD. Adderall is available in both immediate-release (IR) and extended-release (ER) forms, and Methylphenidate ER comes in various formulations, including tablets, capsules, and chewable tablets. Adderall is often preferred for adults, while methylphenidate products are commonly recommended for children and adolescents. Both medications have a risk of misuse and dependency and can cause side effects like trouble sleeping and loss of appetite. However, methylphenidate offers more formulation options, which can be beneficial if you have trouble swallowing pills. Both medications require careful monitoring by your prescriber to manage potential side effects and interactions with other medications.

Adderall

 

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methylphenidate ER

 

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Summary for Adderall

Prescription only

Adderall is a stimulant medication that's used to treat attention deficit-hyperactivity disorder (ADHD) and narcolepsy in adults and children. It contains the instant-release (IR) forms of dextroamphetamine and amphetamine salts. Adderall is available as a brand-name and lower-cost generic tablet that's taken by mouth. Your psychiatrist will adjust the dosage for you based on how well the medication works for you. Common side effects include trouble sleeping and loss of appetite.

Indications for Adderall

Pros and Cons for Adderall

Pros

Cons

  • Has a risk of misuse and dependency
  • A controlled medication, so there are special requirements for getting the prescription filled
  • Dose needs to be raised and lowered slowly to avoid side effects and withdrawal symptoms
  • Not available as a liquid or patch form (unlike methylphenidate (Ritalin))

Common Side Effects for Adderall

  • Upset stomach
  • Lower appetite
  • Weight loss
  • Nervousness
  • Changes in mood
  • Trouble sleeping

Warnings for Adderall

  • Misuse and addiction
  • Dependence and withdrawal
  • Serious heart problems
  • Aggressive behavior and psychosis
  • Slowed growth in children
  • Seizures
  • Blood circulation problems (such as Raynaud's phenomenon)
  • Serotonin syndrome
  • Drug interactions

Summary for Concerta

Prescription only

Methylphenidate extended-release (ER) is a first-choice option for people with attention deficit-hyperactivity disorder (ADHD). This once-daily medication can start to work within 2 hours and can last throughout the day. Methylphenidate ER can cause difficulty sleeping and a loss of appetite. It also has a potential risk of misuse and dependency and is thus a controlled substance.

Indications for Concerta

  • Attention-deficit/hyperactivity disorder (ADHD)

Pros and Cons for Concerta

Pros

  • First-choice medication for ADHD
  • Taken only once per day
  • Available in many different forms (e.g., pills, chewable tablet, liquid)
  • Some brands available in lower-cost generic form
  • Can be prescribed for children as young as 6 years old

Cons

  • Has a risk of misuse and dependency
  • A controlled medication, so there are special requirements for getting the prescription filled
  • Dose needs to be raised and lowered slowly to avoid bothersome side effects like distress and trouble sleeping
  • Not the best choice for pregnant or breastfeeding females or people with heart conditions
  • Can interact with certain blood pressure medications and depression medications

Common Side Effects for Concerta

Side effects might differ depending on the formulation and brand. In general:

Warnings for Concerta

  • Misuse and dependence
  • Serious heart problems
  • Changes in behavior or thoughts
  • Prolonged and painful erection
  • Blood circulation problem (Raynaud's phenomenon)
  • Slowed growth in children
  • Serotonin syndrome
  • Drug interactions

Prices with our coupons for Adderall vs. Concerta

Price Card Drug Icon
Amphetamine Salt Combo30 tablets / 20mg
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Methylphenidate ER30 tablets / 36mg
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