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Opioid Antagonist / Atypical Antidepressant Combinations

Opioid antagonist / atypical antidepressant combination drugs are used in combination with diet and exercise to help with weight loss in obese or overweight patients. They work by decreasing appetite and controlling food cravings.

Why are opioid antagonist atypical antidepressant combinations prescribed?

  1. Weight loss (100%)

Key takeaways

Opioid antagonist and atypical antidepressant combinations are used to treat obesity. This medication combination is thought to act on areas of your brain that control hunger and your reward system, making you less hungry and educing food cravings. An example is naltrexone/bupropion (Contrave).

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Contrave

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Contrave (naltrexone/bupropion) is used to promote and maintain weight loss in obese adults or overweight adults who have weight related medical problems. Contrave is a opioid antagonist/atypical antidepressant combination drug, which works by effecting parts of your brain that are responsible for appetite control and the reward system. Contrave is available as an 8mg/90mg tablet. There are currently no generic alternatives to Contrave. It is covered by most Medicare and insurance plans.
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Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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