Skip to main content

Histamine-3 Antagonists/Inverse Agonists

Histamine-3 Antagonists/Inverse Agonists are used to improve wakefulness and decrease the number of cataplexy attacks in people with narcolepsy. They work by increasing the synthesis and release of histamine.

Why are histamine 3 antagonists inverse agonists prescribed?

  1. Narcolepsy (100%)

Key takeaways

Histamine 3 antagonists / inverse agonists are used to treat narcolepsy, excessive daytime sleepiness, and cataplexy. These medications work by raising histamine levels in the brain, which helps to increase wakefulness and alertness. They are typically available in oral form. An example of this type of medication is pitolisant (Wakix). You can take these medications as prescribed to help manage your symptoms effectively.

Prices for popular Histamine-3 Antagonists/Inverse Agonists medications
Viewing 1 of 1 medications
tablet icon

Wakix

Wakix (pitolisant) is used to treat narcolepsy in adult and pediatric patients. There are currently no generic alternatives to Wakix. It may be covered by your Medicare or insurance plan, but some pharmacy coupons or cash prices could help offset the cost.
See pricesMore info
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

Subscribe and save

Get prescription saving tips and more from GoodRx Health. Enter your email to sign up

By signing up, I agree to GoodRx’s Terms of Use and Privacy Policy, and to receive marketing messages from GoodRx.

Compare other Histamine-3 Antagonists/Inverse Agonists drugs

Wakix vs AdderallWakix vs NuvigilWakix vs SunosiWakix vs XyremAdderall vs Concerta

Browse medications

View All
Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.
ABCDEFGHIJKLMNOPQRSTUVWXYZ