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Direct-Acting Oral Anticoagulants

Direct-acting oral anticoagulants are used to reduce the risk of stroke and treat deep vein thrombosis, pulmonary embolism, peripheral artery disease, coronary artery disease, and atrial fibrillation. They work by thinning the blood to prevent blood clots from forming.

Why are direct acting oral anticoagulants prescribed?

  1. Deep Vein Thrombosis (28%)
  2. Atrial Fibrillation (28%)
  3. Stroke Risk Reduction (26%)
  4. Pulmonary Embolism (12%)
  5. Peripheral Artery Disease (3%)
  6. Coronary Artery Disease (3%)

Key takeaways

Direct-acting oral anticoagulants (DOACs) are used to treat and prevent blood clots, such as a deep vein thrombosis (DVT) or pulmonary embolism (PE). They're commonly prescribed after surgery or if you have a health condition that makes blood clots more likely, such as atrial fibrillation (a type of irregular heartbeat). Examples of DOACs include apixaban (Eliquis), rivaroxaban (Xarelto), and dabigatran (Pradaxa).

Prices for popular Direct-Acting Oral Anticoagulants medications
Viewing 5 of 5 medications
Pradaxa (dabigatran) is used to lower the chance of stroke in people with atrial fibrillation. Pradaxa is less popular than other anticoagulants. There are currently generic alternatives to Pradaxa.

Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Pradaxa is covered by most Medicare and insurance plans.
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Eliquis

as low as$587
Eliquis (apixaban) is used to lower the chance of stroke in people with a medical condition called atrial fibrillation. Eliquis is a direct acting anticoagulant, which works by thinning the blood to prevent blood clots from forming. The most common form of Eliquis is a 2.5mg tablet. It is also avalible as a 5mg tablet. There are currently no generic alternatives for Eliquis. It is covered by some Medicare and insurance plans, but some pharmacy coupons, manufacturer programs, or cash prices may be lower.
Xarelto (rivaroxaban) is an anticoagulant blood thinner used to treat and prevent blood clots that are related to certain conditions involving the heart and blood vessels. Xarelto is a direct acting oral anticoagulant which works by thinning the blood to prevent blood clots from forming. The most common form of Xarelto is a 20mg tablet. It is also avalible as a titration pack and a bottle of oral solution. There are currently no generic alternatives for Xarelto. It is covered by some Medicare and insurance plans, but some pharmacy coupons, manufacturer programs, or cash prices may be lower.
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Savaysa

as low as$446
EDOXABAN prevents and treats blood clots. It is also used to lower the risk of stroke in people with Afib (atrial fibrillation). It belongs to a group of medications called blood thinners.
Apixaban is part of the Direct-Acting Oral Anticoagulants class and treats Deep Vein Thrombosis, Stroke Risk Reduction and Pulmonary Embolism. Direct-acting oral anticoagulants are used to reduce the risk of stroke and treat deep vein thrombosis, pulmonary embolism, peripheral artery disease, coronary artery disease, and atrial fibrillation.

They work by thinning the blood to prevent blood clots from forming. Apixaban is only available as a generic drug.
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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