
capsaicin
Capsaicin is a medication that can be applied to the skin (topical) to help relieve minor aches and pains. It's available over the counter (OTC) as a brand-name or lower-cost generic medication. It comes as a cream, liquid, and patch. Capsaicin is made from a chemical that comes from chili peppers, so it can cause a slight burning sensation when applied.
What is Capsaicin?
What is Capsaicin used for?
Relief of minor aches and pains in the muscles and joints caused by:
- Arthritis
- Backache
- Strains
- Sprains
- Bruises
How Capsaicin works
Capsaicin is a topical analgesic. It relieves pain when applied to the skin by acting as a counterirritant. This means that it activates (wakes up) pain sensors in the skin, which then causes them to be less sensitive to other pain signals.
Drug facts
| Common Brands | Capzasin-HP, Salonpas-Hot |
|---|---|
| Drug Class | Topical analgesic |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | Lower-cost generic available |
| Availability | Over-the-counter |
Side effects of Capsaicin
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Burning sensation
- Itching
Less Common Side Effects
- Rash
- Skin irritation
- Skin redness
Capsaicin serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious skin burns: pain, swelling, blistering of the skin
The following Capsaicin side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common - all forms
Burning, itching, dryness, pain, redness, swelling, or soreness at the application site
Less common - all forms
Body aches or pain
chills
difficulty with breathing
dry or productive cough
ear congestion
headache
loss of voice
stuffy or runny nose
tightness in the chest
unusual tiredness or weakness
Less common - patch only
Blurred vision
breakdown of the skin
dizziness
nervousness
pain in the arms or legs
pounding in the ears
slow or fast heartbeat
Incidence not known - patch only
Bloating or swelling of the face, arms, hands, lower legs, or feet
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
increased sensitivity to pain or touch
scarring of the skin
stabbing pain
throat irritation
unusual weight gain or loss
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known - patch only
Abnormal skin odor
change in or loss of taste
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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Pros and cons of Capsaicin
Pros
- Available OTC as a lower-cost generic
- Can be applied directly to the painful area
- Comes as a patch, cream, and liquid
- Patch can be worn for up to 8 hours
- Generally well-tolerated with few side effects
Cons
- Can't be used in people who are allergic to chili peppers
- Can't be applied to irritated or damaged skin
- Can cause irritation if it makes contact with the eyes, mouth, or nose
- Can cause your skin to be more sensitive to sunlight
- Patch won't stick well to damp skin
Pharmacist tips for Capsaicin
- You can test capsaicin on your skin to see how you react to it before using it on a larger area. Apply a thin layer to a small area of skin and leave it on for 24 hours. A mild burning sensation is normal. You can continue to use the medication as directed by the packaging if your reaction is tolerable.
- For the cream or gel, apply a thin layer and gently rub it in until it's fully absorbed.
- For the liquid, place the applicator on your skin, press firmly, and hold to release liquid. Rub the liquid well into the painful area until it's completely absorbed.
- For the patch, clean and fully dry the affected area. You can trim the patch to better fit the area you're treating. Be sure to trim the patch before removing its backing. Remove the backing from the patch and apply it directly to the painful area. Throw the patch away after a single use. Make sure to fold the sticky sides of your used patch together before throwing it away. This helps prevent accidental exposure of any remaining medication on the patch to children and pets.
- Wash hands well with soap and water right after applying capsaicin to avoid spreading the medication to other areas of the body like the eyes or mouth. You can also wear gloves when applying to avoid getting the medication on your hands. If you're using this medication to treat your hands, wait 30 minutes before washing them. And be sure not to touch your face before you've washed your hands.
- Warm or hot water, direct sunlight, heat from hair dryers or heat lamps, and intense exercise can put you more at risk for burning and itching after applying capsaicin. Don't apply this medication right before or after a hot shower or bath, intense exercise, or being exposed to direct sunlight or heat.
- Capsaicin can make your skin more sensitive to sunlight. Try to avoid long periods of sun exposure. If you're going to be in the sun, wear sunscreen and protective clothing that covers the skin you've treated with capsaicin.
- Capsaicin comes from a chemical that's found in chili peppers. Talk to your provider before using this medication if you're allergic to chili peppers.
Risks and warnings for Capsaicin
Capsaicin can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk of serious burns
- Risk factors: Covering the application area | Applying heat to the application area
Although rare, capsaicin can cause serious skin burns. If this happens, it usually occurs within 24 hours of the first use. Sometimes, they can be so severe that the event requires hospitalization. Stop using this medication if you experience pain, blistering, or swelling at the site of application and get medical help right away.
Capsaicin dosage
Interactions between Capsaicin and other drugs
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
How much does Capsaicin cost?
$10.22
What are alternatives to Capsaicin?
Relief of minor aches and pains in the muscles and joints caused by:
News about Capsaicin


