The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Lower blood cell counts (up to 79%)
- Fatigue (77%)
- Signs of stress to the kidney on blood tests (up to 69%)
- Signs of stress to the liver on blood tests (up to 66%)
- High blood sugar levels (52%)
- Nausea (37%)
- Muscle, bone, or joint pain (33%)
- Not feeling hungry (33%)
- Constipation (31%)
- Feeling short of breath (31%)
Zepzelca serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Low blood cell counts: unusual bleeding or bruising, fever, feeling very tired
- Liver injury: pain on the right side of the stomach, yellowing of the eyes or skin, dark or brown urine
- Severe muscle damage: dark brown urine, severe muscle pain, tiredness
Source: DailyMed
The following Zepzelca side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
- Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
- Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
- Muscle injury—unusual weakness or fatigue, muscle pain, dark yellow or brown urine, decrease in amount of urine
- Painful swelling, warmth, or redness of the skin, blisters or sores at the infusion site
- Unusual bruising or bleeding
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Constipation
- Cough
- Diarrhea
- Fatigue
- Loss of appetite
- Nausea
