The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Low blood cell counts
- Nausea
- Vomiting
- Diarrhea
- Mouth ulcers
Less Common Side Effects
- Liver problems
- Rash
Melphalan serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious infections: repeated fevers, chills, cough, trouble breathing, severe diarrhea, vomiting, painful or frequent urination
- Serious bleeds: bleeding or bruising that doesn’t stop or go away, large amount of bleeding, blood in the urine, throwing up blood, bloody or black and tarry stool
- Allergic reactions: throat tightness, trouble breathing, cough, itching or hives, flushing, swelling, chest pain, fast heartbeat, dizziness, fainting
Source: DailyMed
The following Melphalan side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
More common
chills
cough or hoarseness
lower back or side pain
painful or difficult urination
shortness of breath
sores, ulcers, or white spots on the lips or in the mouth
swollen glands
unusual bleeding or bruising
unusual tiredness or weakness
Incidence not known
Abdominal or stomach pain
absent, missed, or irregular menstrual periods
back or leg pains
bleeding gums
bloated abdomen or stomach
blurred vision
clay-colored stools
confusion
dark urine
difficult or labored breathing
difficulty with swallowing
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fast, pounding, or irregular heartbeat or pulse
general body swelling
headache
indigestion
light-colored stools
loss of appetite
noisy breathing
nosebleeds
pain and fullness in right upper abdomen or stomach
pale skin
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
reddening of the skin, especially around the ears
sweating
swelling of eyes, face, hands, ankles, feet, or lower legs
tightness in the chest
unpleasant breath odor
unusual lumps or masses
vomiting of blood
weight gain or loss
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
Blue-green to black skin discoloration
hair loss or thinning of the hair
pain, redness, soreness, or sloughing of the skin at the injection site
sores, welting, or blisters
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
