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Leukeran

Leukeran Side Effects

Jenny Zhang, PharmD, BCOPConnie Zheng, PharmD
Reviewed by Jenny Zhang, PharmD, BCOP, Connie Zheng, PharmD
Last reviewed on July 18, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Low blood cell counts

Less Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Mouth ulcers
  • Tremors
  • Muscle spasms
  • Feeling agitated or confused
  • Allergic reaction (hives or swelling)

Leukeran serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious infections: repeated fevers, chills, sweating, cough, trouble breathing, sore throat, stuffy nose, severe diarrhea, vomiting, painful or frequent urination
  • Serious bleeds: bleeding or bruising that doesn’t stop or go away, large amount of bleeding, blood in the urine, throwing up blood, bloody or black and tarry stool
  • Seizures
  • Severe skin reaction: rash, blistering or peeling of skin, hives, fever, painful sores in your mouth or around your eyes
  • Liver damage: dark urine, right-sided stomach pain, yellowing of the eyes or skin, tiredness, loss of appetite, nausea, vomiting

Source: DailyMed

The following Leukeran side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Black, tarry stools

bleeding gums

blood in the urine or stools

chest pain

cough or hoarseness, accompanied by fever or chills

fever or chills

lower back or side pain, accompanied by fever or chills

painful or difficult urination, accompanied by fever or chills

pinpoint red spots on the skin

shortness of breath

sores, ulcers, or white spots on the lips or in the mouth

swollen glands

troubled breathing with exertion

unusual bleeding or bruising

unusual tiredness or weakness

Less common

Itching

joint pain

large, swollen hives

skin rash

swelling of the feet or lower legs

Rare

Blistering, peeling, or loosening of the skin

diarrhea

muscle pain

muscle twitching

red skin lesions, often with a purple center

red, irritated eyes

seizures

shakiness and unsteady walk

shakiness in the legs, arms, hands, or feet

sore throat

sudden jerky movements of the body

unsteadiness, trembling, or other problems with muscle control or coordination

Incidence not known

Abdominal or stomach pain or tenderness

bone pain

clay colored stools

dark urine

decreased appetite

difficult breathing

headache

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

loss of appetite

trouble getting pregnant

troubled or quick, shallow breathing

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Changes in menstrual period

nausea and vomiting

Rare

Anxiety

confusion

dry mouth

hyperventilation

irregular heartbeats

irritability

no muscle tone or movement

restlessness

seeing, hearing, or feeling things that are not there

trouble sleeping

Incidence not known

Hives or welts

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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