The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Lower white blood cells (up to 99%)
- Lower hemoglobin levels (up to 88%)
- Lower platelet levels (86%)
- Nausea (75%)
- Tiredness (57%)
- Vomiting (40%)
- Diarrhea (37%)
- Fever (34%)
- Constipation (29%)
- Lower appetite (23%)
- Cough (22%)
- Headache (21%)
Less Common Side Effects
- Chills
- Weakness
- Dizziness
- Mouth sores
- Stomach pain
- Indigestion
- Acid reflux
- Swelling in the legs, ankles, or feet
- Weight loss
- Dehydration
- Back pain
- Shortness of breath
- Trouble sleeping
- Infection (e.g., shingles, upper respiratory, urinary tract)
- Rash
Note: Side effects were reported by people with B-cell NHL taking bendamustine (Treanda). Side effects are expected to be similar for Bendeka (bendamustine).
Bendeka serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Low white blood cell count and risk of infection: fever, chills, cough, muscle aches, very fast heartbeat, severe tiredness
- Low platelets: easy bruising or bleeding, nosebleeds, blood in urine, blood in stool
- Progressive multifocal leukoencephalopathy (PML): confusion, weakness, clumsiness, trouble speaking, trouble walking
- Infusion reaction or allergic reaction: fever, chills, itching, rash, trouble breathing
- Serious skin reaction: rash, painful blisters, skin wounds, peeling skin, fever, sore throat, body aches
- Serious liver problems: yellow skin, yellow eyes, sudden stomach pain, swollen belly
Source: DailyMed
The following Bendeka side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
More common
Black, tarry stools
bleeding gums
blood in the urine or stools
chills
cough or hoarseness
headache
joint pain, stiffness, or swelling
lack or loss of strength
lower back, side, or stomach pain
muscle aches
painful or difficult urination
pale skin
pinpoint red spots on the skin
stuffy or runny nose
swelling of the feet or lower legs
swollen glands
troubled breathing with exertion
ulcers, sores, or white spots in the mouth
unusual bleeding or bruising
unusual tiredness or weakness
vomiting
Less common
Burning or stinging of the skin
fast heartbeat
irritation
painful cold sores or blisters on the lips, nose, eyes, or genitals
redness of the skin
stiffness or swelling
swelling of the eyelids, face, lips, hands, or feet
tightness in the chest
troubled breathing or swallowing
Incidence not known
Blistering, flaking, or peeling of the skin
bluish color
changes in skin color
dizziness
pain, tenderness, or swelling of the foot or leg
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
red skin lesions, often with a purple center
red, irritated eyes
weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Decreased weight
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
