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Melphalan

Melphalan Dosage

Jenny Zhang, PharmD, BCOPCydnee Ng, PharmD
Reviewed by Jenny Zhang, PharmD, BCOP, Cydnee Ng, PharmD
Last reviewed on April 7, 2023

The average cost for 30 tablets of 2mg of Melphalan is $278.59 with a free GoodRx coupon. This is 29.62% off the average retail price of $395.85.

tabletTablet

Dosage

Quantity

Price as low as

Price per unit

2mg

30 tablets

$278.59

$9.29

Typical dosage for Melphalan

Multiple myeloma

  • Tablets: The typical dose is 6 mg by mouth once a day for 2 to 3 weeks, followed by an off period for up to 4 weeks. You’ll need to get lab work done regularly during this time so your provider can check your blood cell counts. Once your blood cell counts are trending up, the recommended maintenance dose is 2 mg daily.
  • Intravenous (IV): Your provider will calculate your dose of melphalan (Alkeran) using your body surface area (BSA, in units of m2), which takes into account your body weight and height. The typical dose is 16 mg/m2 given as an infusion through the vein every 2 weeks for 4 doses, followed by an off period. Once your blood cell counts are trending up, you’ll receive melphalan (Alkeran) every 4 weeks.

Ovarian cancer

  • Tablets: The dose depends on your weight. One typical dosing regimen is 0.2 mg/kg by mouth once a day for 5 days per cycle. Each cycle is repeated every 4 to 5 weeks depending on your blood cell counts.

Your dose might differ if you have kidney problems.

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