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Vigabatrin

Vigabatrin Side Effects

Robert Chad Hakim, PharmD, BCCCPAllison Gourley, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Allison Gourley, PharmD
Last reviewed on June 20, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Adults

  • Headache (33%)
  • Dizziness (24%)
  • Tiredness (23%)
  • Drowsiness (22%)
  • Uncontrolled shaking (15%)
  • Common cold symptoms (14%)
  • Blurred vision (13%)
  • Eye twitching (13%)
  • Diarrhea (10%)
  • Nausea (10%)
  • Joint pain (10%)
  • Abnormal coordination (6%)

Children age 3 to 16 years (for complex partial seizures)

  • Weight gain (15%)
  • Upper respiratory tract infection (e.g., cough, common cold; 15%)
  • Tiredness (10%)

Children age 1 month to 2 years (for infantile spasms)

  • Upper respiratory tract infection (up to 51%)
  • Middle ear infection (up to 44%)
  • Fever (up to 29%)
  • Irritable behavior (up to 23%)
  • Vomiting (up to 20%)
  • Sleepiness (up to 19%)

Less Common Side Effects

  • Vomiting
  • Constipation
  • Pain in the hands or feet
  • Swelling in the hands or feet due to fluid buildup (edema)
  • Weight gain
  • Double vision
  • General weakness
  • Flu-like symptoms
  • Memory problems
  • Difficulty paying attention
  • Tingling sensation
  • Feeling irritable
  • Depression
  • Menstrual cramps (in women)
  • Rash

Vigabatrin serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Permanent vision loss
  • Suicidal thoughts or behaviors

Source: DailyMed

The following Vigabatrin side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Change in vision such as blurry vision, seeing halos around lights, vision loss
  • Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
  • Pain, tingling, or numbness in the hands or feet
  • Thoughts of suicide or self-harm, worsening mood, feelings of depression

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

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