The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Sleepiness (17%)
- Dizziness (13%)
- Low appetite (13%)
- Headache (10%)
- Nausea (9%)
- Agitation or irritability (9%)
- Fatigue (8%)
- Tiredness (7%)
- Stomach pain (6%)
- Confusion (6%)
- Depression (6%)
- Trouble sleeping (6%)
- Problems with concentration or memory (6%)
- Clumsy movement (6%)
- Double vision (seeing double; 6%)
Less Common Side Effects
- Diarrhea
- Indigestion
- Constipation
- Kidney stones
- Dry mouth
- Speech problems
- Tingling in your arms, hands, or feet
- Weight loss
- Slow thinking
- Anxiety or nervousness
- Rash
- Changes in taste
- Flu-like symptoms
Zonisamide serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious allergic reaction: swelling of the face and neck area, trouble breathing, widespread skin redness or rash, fever
- Serious skin reaction: blisters, skin peeling, fever, flu-like symptoms
- Suicidal thoughts or behavior
- Unusual changes in mood, thoughts, or behavior
- Heat stroke: sweating less than usual; fever; hot, dry, red skin; confusion
- Eye problems: sudden blurry vision, trouble seeing far away, sudden eye pain or eye redness
- Kidney problems: sudden back pain, stomach pain, blood in the urine
- High acid levels: fast breathing, fast heartbeat, tiredness, confusion, loss of appetite, nausea, weakness
Source: DailyMed
The following Zonisamide side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Discouragement
double vision
feeling sad or empty
irritability
lack of appetite
loss of interest or pleasure
mood or mental changes
shakiness or unsteady walking
tiredness
trouble with concentrating
trouble with sleeping
Less common
Agitation
bruising
delusions
hallucinations
large, flat blue or purplish patches on the skin
rash
Incidence not known
Blurred vision
change in near or distance vision
difficulty in focusing eyes
increase in frequency of seizures
swelling of the face
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Abdominal or stomach pain
difficulty with memory
dizziness
double vision
headache
loss of appetite
restlessness
sleepiness
unusual drowsiness
unusual tiredness or weakness
Less common
Aching muscles or joints
acid or sour stomach
bad, unusual, or unpleasant taste in the mouth
belching
change in taste
chills
difficulty with speaking
difficulty with thinking
general ill feeling
headache
indigestion
mental slowness
nervousness
runny or stuffy nose
tingling, burning, or prickly feelings on the skin
uncontrolled, back and forth, or rolling eye movements
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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