The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Low blood cell counts (21-52%)
- Tiredness (50%)
- Nausea (41%)
- Numbness or tingling sensation in hands and feet (39%)
- Nosebleeds (39%)
- Hair loss (39%)
- Eye irritation (37%)
- Bleeding (32%)
- Dry eyes (29%)
- Abnormal kidney tests (29%)
- Abnormal blood clotting tests (26%)
- Rash (25%)
- Diarrhea (25%)
- Abnormal liver tests (17-24%)
- Constipation (23%)
- Stomach pain (23%)
- Corneal problems (21%)
- Muscle pain (21%)
Less Common Side Effects
- Itching
- Vomiting
- Eye itching or inflammation
- Fevers
- Joint pain
- Pain in the arms and legs
- Decreased appetite
- Urinary tract infections
- Weight loss
Tivdak serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Nerve damage (neuropathy): tingling in the hands or feet, numbness, muscle weakness or twitching, loss of grip, loss of pain or touch
- Serious bleeds: bleeding or bruising that won’t stop or go away, blood in the urine, bloody or black and tarry stools, heavy vaginal bleeding, coughing up blood
- Lung problems: shortness of breath, cough, difficulty breathing
- Severe eye problems: vision changes, blurry vision, vision loss, corneal inflammation or ulcers, eyelid inflammation, dry eyes, red eyes
- Severe allergic or skin problems: rash, peeling of skin, hives, trouble breathing, painful sores or ulcers
Source: DailyMed
The following Tivdak side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
- Dry cough, shortness of breath or trouble breathing
- Eye pain, redness, irritation, or discharge with blurry or decreased vision
- Frequent or severe nosebleeds
- Heavy vaginal bleeding
- Pain, tingling, or numbness in the hands or feet
- Rash, fever, and swollen lymph nodes
- Redness, blistering, peeling, or loosening of the skin, including inside the mouth
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
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