Tretinoin (tretinoin emollient, refissa, Renova) is an expensive drug used on the skin to treat mild to moderate acne. This drug is less popular than comparable drugs. It is available in multiple brand and generic versions. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.

Get Refissa for as low as $135.05, which is 52% off the average retail price of $278.97 for the most common version, by using a GoodRx coupon.