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Aklief (trifarotene) is applied to the skin to treat acne. Aklief is slightly less popular than other retinoids. There are currently no generic alternatives to Aklief.
GoodRx has partnered with Inside RX and Galderma Laboratories to reduce the price for this prescription. Check our savings tips for co-pay cards, assistance programs, and other ways to reduce your cost. Aklief is not covered by most Medicare and insurance plans.
Get Aklief for as low as $613.13, which is 33% off the average retail price of $917.99 for the most common version, by using a GoodRx coupon.

| Dosage | Quantity | Retail price | GoodRx price |
|---|
| 45g of 0.005% | 1 pump | $918.99 | $613.13 |
GoodRx coupon prices last updated on 04/18/26.