Claritin-D (loratadine / pseudoephedrine) is an over-the-counter medication that's used to relieve allergies and congestion. It's available as a 24-hour tablet that's taken once per day and a 12-hour tablet that's taken twice per day. Possible side effects include headache, dry mouth, drowsiness, and difficulty sleeping. There are lower-cost generic and brand versions of the medication available. You can find Claritin-D (loratadine / pseudoephedrine) at the pharmacy counter (or behind the counter).
Short-term relief of allergy symptoms:
Claritin-D (loratadine / pseudoephedrine) is a combination of two medications that work together to relieve allergy symptoms.
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Contact your healthcare provider immediately if you experience any of the following.
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
While uncommon, it's possible for Claritin-D (loratadine / pseudoephedrine) to make you drowsy (sleepy). A study showed that 6% of people taking the 24-hour tablet of Claritin-D (loratadine / pseudoephedrine) once daily felt drowsy, sleepy, or sluggish. In general, Claritin-D (loratadine / pseudoephedrine) is less likely to cause drowsiness than other antihistamines like diphenhydramine (Benadryl).
Don't take other medications that have an antihistamine or decongestant (e.g., pseudoephedrine, phenylephrine). Claritin-D (loratadine / pseudoephedrine) already contains an antihistamine and a decongestant. Using multiple products that contain these types of medications can raise your risk for overdose and side effects. Also talk with your provider first before taking Claritin-D (loratadine / pseudoephedrine) with medications that have stimulant-like effects because this combination can raise your risk for dangerously high blood pressure. Since it's possible for Claritin-D (loratadine / pseudoephedrine) to make you feel drowsy, consult with a provider if you need to take medications that can raise your risk of drowsiness even more (e.g., opioids, sleep medications). If you're not sure whether you're taking a medication that interacts with Claritin-D (loratadine / pseudoephedrine), ask your provider or pharmacist.
Yes, Claritin-D (loratadine / pseudoephedrine) is an over-the-counter medication that you can find at local pharmacies. But it's actually located behind the counter, which means that you'll need to go to the pharmacy counter to purchase it. You'll be asked to present photo identification and sign when you buy it. This is required because Claritin-D (loratadine / pseudoephedrine) can potentially be misused. Ask your pharmacist to help you locate Claritin-D (loratadine / pseudoephedrine) in the pharmacy.
Claritin is the brand name for loratadine, an antihistamine that treats allergy symptoms like itchy or watery eyes, runny nose, and sneezing. Claritin-D 24-Hour and Claritin-D 12-Hour are brand names for tablets with both loratadine and pseudoephedrine. Because it contains pseudoephedrine (a decongestant), Claritin-D is more useful than Claritin for people who also have nasal or sinus congestion in addition to itchy or watery eyes, runny nose, and sneezing.
If you're pregnant, thinking of getting pregnant, or breastfeeding, don't take Claritin-D (loratadine / pseudoephedrine) until you've talked to your provider first. This medication contains pseudoephedrine. The safety of pseudoephedrine during pregnancy isn't completely clear because of inconsistent results from limited data. Your provider will probably recommend that you avoid using Claritin-D (loratadine / pseudoephedrine) at least during the first 3 months of pregnancy because of the potential risk of harm to babies. Additionally, pseudoephedrine can potentially dry up your breast milk production and might cause your baby to be irritable. For these reasons, it's a good idea to discuss the risks and benefits of Claritin-D (loratadine / pseudoephedrine) with your provider first.
Don't take Claritin-D (loratadine / pseudoephedrine) for longer than 7 days. If your symptoms haven't gotten better after 7 days of using the medication or if you develop a fever, you should stop using Claritin-D (loratadine / pseudoephedrine). Contact your provider because these could be signs of a more serious medical problem. They can make sure you get appropriate treatment.
It depends on which Mucinex product you choose to use. Mucinex is a brand that makes multiple products to treat cold and flu symptoms. Some of these products are single-ingredient medications, and others are combination products. Depending on the product, Mucinex can contain acetaminophen for pain, tripolidine (an antihistamine) for cold symptoms, and phenylephrine (a decongestant). It's not recommended to take a Mucinex product with Claritin-D (loratadine / pseudoephedrine) if that product has phenylephrine or triprolidine. Claritin-D (loratadine / pseudoephedrine) already has an antihistamine (loratadine) and a decongestant (pseudoephedrine). Taking Claritin-D (loratadine / pseudoephedrine) with another product containing an antihistamine or decongestant can raise your risk of side effects, such as high blood pressure, headache, and trouble urinating. Talk with your pharmacist if you have trouble choosing a Mucinex product that you can take with Claritin-D (loratadine / pseudoephedrine).
In general, Claritin-D (loratadine / pseudoephedrine) can take 30 minutes to over 1 hour to start working. Loratadine generally works within 1 to 3 hours, while pseudoephedrine takes about 30 minutes to 1 hour. So it's possible that you might feel start to feel some of your allergy symptoms get better sooner than others.
Claritin-D (loratadine / pseudoephedrine) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Claritin-D (loratadine / pseudoephedrine) can raise your heart rate and blood pressure, even at recommended doses. If you have a history of heart problems or high blood pressure, ask your provider if Claritin-D (loratadine / pseudoephedrine) is safe for you before using this medication. If you get severe headaches, nosebleeds, difficulty breathing, irregular heartbeat, or chest pain while taking Claritin-D (loratadine / pseudoephedrine), stop taking it and get medical attention right away. These can be signs of seriously high blood pressure.
Claritin-D (loratadine / pseudoephedrine) might make you drowsy, which can affect your ability to focus, think, or react. This side effect is more likely to happen if you drink alcohol while taking this medication or take other medications that also cause sleepiness (e.g., opioids, certain anxiety medications, sleep medications). Don't drive or operate machinery until you know how Claritin-D (loratadine / pseudoephedrine) affects you.
Don't take Claritin-D (loratadine / pseudoephedrine) if you have any of the risk factors listed above unless your provider said it's safe to do so. Taking Claritin-D (loratadine / pseudoephedrine) can worsen the symptoms of certain conditions. And sometimes, having certain other medical conditions can raise your risk of side effects from Claritin-D (loratadine / pseudoephedrine). Make sure your provider knows about all medical conditions you have or have had in the past before starting Claritin-D (loratadine / pseudoephedrine). They can discuss with you about whether this medication is safe for you to take.
Claritin-D (loratadine / pseudoephedrine) contains an antihistamine (loratadine) and a decongestant (pseudoephedrine), which are found in many other over-the-counter products. Using more than one medication containing an antihistamine (including products used on the skin) or a decongestant can lead to an accidental overdose and cause serious side effects. These side effects can include high blood pressure, sleepiness, dizziness, seizures, hallucinations (seeing things that aren't real), or even death.
Tell your provider or pharmacist about all the medications you take before starting Claritin-D (loratadine / pseudoephedrine) to make sure it's safe for you. Don't start any new medications while taking Claritin-D (loratadine / pseudoephedrine) without talking to your provider or pharmacist. To prevent an accidental overdose, read package labels carefully. If you're not sure if a product has an antihistamine or a decongestant, ask your pharmacist. If you or your loved one experiences an accidental overdose, get medical help right away or contact a poison control center at 1-800-222-1222.
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 24 hour | 30 tablets | $19.32 | $0.64 |
| 12 hour | 60 tablets | $26.43 | $0.44 |
24-hour tablet: Each tablet contains 10 mg of loratadine and 240 mg of pseudoephedrine.
12-hour tablet: Each tablet contains 5 mg of loratadine and 120 mg of pseudoephedrine.
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Claritin-D (loratadine / pseudoephedrine) will not be safe for you to take.
Short-term relief of allergy symptoms: