What is Lenvima?

They need to know if you have any of these conditions:

• Bleeding disorder
• Dental or gum disease
• Having or recent surgery
• Heart attack
• Heart disease
• Headaches
• High blood pressure
• High thyroid levels
• History of a connection between 2 or more body parts that do not usually connect (fistula)
• History of a tear in your stomach or intestines
• Irregular heartbeat or rhythm
• Kidney disease
• Liver disease
• Low thyroid levels
• Protein in your urine
• Seizures
• Stroke
• Vision problems
• An unusual or allergic reaction to lenvatinib, other medications, foods, dyes, or preservatives
• Pregnant or trying to get pregnant
• Breast-feeding

Take this medicine by mouth. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the capsules whole. If you are unable to swallow the capsules whole, you can mix them with water or apple juice. You can take it with or without food. If it upsets your stomach, take it with food. Keep taking it unless your care team tells you to stop.

When using capsules to make a suspension: Place the number of capsules for your dose in a small container or syringe. If your dose is more than 5 capsules, follow these directions with 3 capsules at a time. Add 3 mL of water or apple juice to the container or syringe. If you will be giving in a feeding tube, only mix with water. After 10 minutes, shake or stir until it is completely dissolved. Do not break or crush the capsules. Drink the mixture or give it through the feeding tube right away. Repeat adding another 2 mL of water or apple juice, shaking or stirring, and drinking the mixture or giving through the feeding tube right away. Repeat this at least 1 more time until you cannot see any more of the mixture left in the container or syringe.

Talk to your care team about the use of this medication in children. Special care may be needed.

If you miss a dose, take it as soon as you can unless it is more than 12 hours late. If it is more than 12 hours late, skip the missed dose. Take the next dose at the normal time.

Keep out of the reach of children and pets.

Store between 20 and 25 degrees C (68 and 77 degrees F). If you make a mixture with water or apple juice, store it in a covered container in the refrigerator at 2 to 8 degrees C (36 to 46 degrees F) for up to 24 hours. Get rid of any unused medication after the expiration date.

To get rid of medications that are no longer needed or have expired:

• Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
• If you cannot return a medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put in the trash, take the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.