The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Low blood cell counts (up to 80%)
- Higher liver enzyme levels (up to 43%)
- Low sodium levels (35%)
- Low calcium levels (31%)
- Tiredness (25%)
- Nausea (25%)
- Muscle, bone, or joint pain (21%)
- Low potassium levels (21%)
- Rash (18%)
- Pneumonia (17%)
- Diarrhea (16%)
Less Common Side Effects
- Hypothyroidism (low thyroid hormone levels)
- Constipation
- Low appetite
- Itchiness
- High blood sugar levels
- Cough
- Injection site reactions
- Numbness or tingling in the arms or legs
Note: Side effects came from adults with lung cancer who were also taking chemotherapy. Side effects might differ for people taking [[EDITOR|DRUG_DISPLAY_NAME]] by itself or with other chemotherapy. They might be different for other types of cancer and for children.
Keytruda Qlex serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious immune-related side effects: rash, blisters, skin peeling, diarrhea, trouble breathing, coughing, chest pain, severe stomach pain, mucus or blood in stool
- Serious reaction during the injection: shivering, chills, flushing, rash, itching, dizziness, fever, throat tightness, trouble breathing, wheezing, swelling of the face
Source: FDA
The following Keytruda Qlex side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Dry cough, shortness of breath or trouble breathing
- Eye pain, redness, irritation, or discharge with blurry or decreased vision
- Heart muscle inflammation—unusual weakness or fatigue, shortness of breath, chest pain, fast or irregular heartbeat, dizziness, swelling of the ankles, feet, or hands
- Hormone gland problems—headache, sensitivity to light, unusual weakness or fatigue, dizziness, fast or irregular heartbeat, increased sensitivity to cold or heat, excessive sweating, constipation, hair loss, increased thirst or amount of urine, tremors or shaking, irritability
- Injection reactions—chest pain, shortness of breath or trouble breathing, feeling faint or lightheaded
- Kidney injury (glomerulonephritis)—decrease in the amount of urine, red or dark brown urine, foamy or bubbly urine, swelling of the ankles, hands, or feet
- Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
- Pain, tingling, or numbness in the hands or feet, muscle weakness, change in vision, confusion or trouble speaking, loss of balance or coordination, trouble walking, seizures
- Rash, fever, and swollen lymph nodes
- Redness, blistering, peeling, or loosening of the skin, including inside the mouth
- Sudden or severe stomach pain, bloody diarrhea, fever, nausea, vomiting
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Bone, joint, or muscle pain
- Diarrhea
- Fatigue
- Loss of appetite
- Nausea
- Skin rash



